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Discovery of novel naphthoquinone derivatives as inhibitors of the tumor cell specific M2 isoform of pyruvate kinase [期刊论文]
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017-09-29, 卷号: 138, 页码: 343-352
Ning, Xianling;  Qi, Hailong;  Li, Ridong;  Li, Yunqiao;  Jin, Yan;  McNutt, Michael A.;  Liu, Junyi;  Yin, Yuxin
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Structural basis of mutant-selectivity and drug-resistance related to CO-1686 [期刊论文]
ONCOTARGET, 2017-08-08, 卷号: 8, 期号: 32, 页码: 53508-53517
Yan, Xiao-E;  Zhu, Su-Jie;  Liang, Ling;  Zhao, Peng;  Choi, Hwan Geun;  Yun, Cai-Hong
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Systematic analysis of gene expression patterns associated with postmortem interval in human tissues [期刊论文]
SCIENTIFIC REPORTS, 2017-07-14, 卷号: 7
Zhu, Yizhang;  Wang, Likun;  Yin, Yuxin;  Yang, Ence
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Structure Based Design of N-(3-((1H-Pyrazolo[3,4-b]pyridin-5-yl)ethynyl)benzenesulfonamides as Selective Leucine-Zipper and Sterile-alpha Motif Kinase (ZAK) Inhibitors [期刊论文]
JOURNAL OF MEDICINAL CHEMISTRY, 2017-07-13, 卷号: 60, 期号: 13, 页码: 5927-5932
Chang, Yu;  Lu, Xiaoyun;  Shibu, Marthandam Asokan;  Dai, Yi-Bo;  Luo, Jinfeng;  Zhang, Yan;  Li, Yingjun;  Zhao, Peng;  Zhang, Zhang;  Xu, Yong;  Tu, Zheng-Chao;  Zhang, Qing-Wen;  Yun, Cai-Hong;  Huang, Chih-Yang;  Ding, Ke
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Structural pharmacological studies on EGFR T790M/C797S [期刊论文]
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2017-06-24, 卷号: 488, 期号: 2, 页码: 266-272
Kong, Lu-Lu;  Ma, Rui;  Yao, Ming-Yu;  Yan, Xiao-E.;  Zhu, Su-Jie;  Zhao, Peng;  Yun, Cai-Hong
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PTEN alpha Modulates CaMKII Signaling and Controls Contextual Fear Memory and Spatial Learning [期刊论文]
CELL REPORTS, 2017-06-20, 卷号: 19, 期号: 12, 页码: 2627-2641
Wang, Pan;  Mei, Fan;  Hu, Jiapan;  Zhu, Minglu;  Qi, Hailong;  Chen, Xi;  Li, Ruiqi;  McNutt, Michael A.;  Yin, Yuxin
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Protein Phosphatase 2A (PP2A) Regulates EG5 to Control Mitotic Progression [期刊论文]
SCIENTIFIC REPORTS, 2017-05-09, 卷号: 7
Liu, Yang;  Zhang, Zhong;  Liang, Hui;  Zhao, Xuyang;  Liang, Ling;  Wang, Guangxi;  Yang, Jingyi;  Jin, Yan;  McNutt, Michael A.;  Yin, Yuxin
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Transcriptional regulators dictate innate lymphoid cell fates [期刊论文]
PROTEIN & CELL, 2017-04-01, 卷号: 8, 期号: 4, 页码: 242-254
Zhong, Chao;  Zhu, Jinfang
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Small-Molecule ROR gamma t Antagonists: One Stone Kills Two Birds [期刊论文]
TRENDS IN IMMUNOLOGY, 2017-04-01, 卷号: 38, 期号: 4, 页码: 229-231
Zhong, Chao;  Zhu, Jinfang
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Organic-Nanowire-SiO2 Core Shell Microlasers with Highly Polarized and Narrow Emissions for Biological Imaging [期刊论文]
ACS APPLIED MATERIALS & INTERFACES, 2017-03-01, 卷号: 9, 期号: 8, 页码: 7385-7391
Feng, Changfu;  Xu, Zhenzhen;  Wang, Xu;  Yang, Hongjuan;  Zheng, Lemin;  Fu, Hongbing
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Antigen Processing in the Endoplasmic Reticulum Is Monitored by Semi-Invariant ab TCRs Specific for a Conserved Peptide-Qa-1(b) MHC Class Ib Ligand [期刊论文]
JOURNAL OF IMMUNOLOGY, 2017-03-01, 卷号: 198, 期号: 5, 页码: 2017-2027
Guan, Jian;  Yang, Soo Jung;  Gonzalez, Federico;  Yin, Yuxin;  Shastri, Nilabh
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A structure-guided optimization of pyrido[2,3-d]pyrimidin-7-ones as selective inhibitors of EGFR(L858R/T790M) mutant with improved pharmacokinetic properties [期刊论文]
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017-01-27, 卷号: 126, 页码: 1107-1117
Yu, Lei;  Huang, Minhao;  Xu, Tianfeng;  Tong, Linjiang;  Yan, Xiao-e;  Zhang, Zhang;  Xu, Yong;  Yun, Caihong;  Xie, Hua;  Ding, Ke;  Lu, Xiaoyun
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Discovery and characterization of a novel irreversible EGFR mutants selective and potent kinase inhibitor CHMFL-EGFR-26 with a distinct binding mode [期刊论文]
ONCOTARGET, 2017-01-01, 卷号: 8, 期号: 11, 页码: 18359-18372
Hu, Chen;  Wang, Aoli;  Wu, Hong;  Qi, Ziping;  Li, Xixiang;  Yan, Xiao-E;  Chen, Cheng;  Yu, Kailin;  Zou, Fengming;  Wang, Wenchao;  Wang, Wei;  Wu, Jiaxin;  Liu, Juan;  Wang, Beilei;  Wang, Li;  Ren, Tao;  Zhang, Shanchun;  Yun, Cai-Hong;  Liu, Jing;  Liu, Qingsong
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Prediction of Protein Lysine Acylation by Integrating Primary Sequence Information with Multiple Functional Features [期刊论文]
JOURNAL OF PROTEOME RESEARCH, 2016-12-01, 卷号: 15, 期号: 12, 页码: 4234-4244
Du, Yipeng;  Zhai, Zichao;  Li, Ying;  Lu, Ming;  Cai, Tanxi;  Zhou, Bo;  Huang, Lei;  Wei, Taotao;  Li, Tingting
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Phosphorylation of PPAR gamma at Ser84 promotes glycolysis and cell proliferation in hepatocellular carcinoma by targeting PFKFB4 [期刊论文]
Oncotarget, 2016-11-22, 卷号: 7, 期号: 47, 页码: 76984-76994
Shu, Yuxin;  Lu, Yan;  Pang, Xiaojuan;  Zheng, Wei;  Huang, Yahong;  Li, Jiahong;  Ji, Jianguo;  Zhang, Can;  Shen, Pingping;  Shu, Yuxin;  Lu, Yan;  Pang, Xiaojuan;  Zheng, Wei;  Huang, Yahong;  Li, Jiahong;  Ji, Jianguo;  Zhang, Can;  Shen, Pingping
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Epistasis and destabilizing mutations shape gene expression variability in humans via distinct modes of action [期刊论文]
HUMAN MOLECULAR GENETICS, 2016-11-15, 卷号: 25, 期号: 22, 页码: 4911-4919
Yang, Ence;  Wang, Gang;  Yang, Jizhou;  Zhou, Beiyan;  Tian, Yanan;  Cai, James J.
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Ibrutinib targets mutant-EGFR kinase with a distinct binding conformation [期刊论文]
ONCOTARGET, 2016-10-25, 卷号: 7, 期号: 43, 页码: 69760-69769
Wang, Aoli;  Yan, Xiao-E;  Wu, Hong;  Wang, Wenchao;  Hu, Chen;  Chen, Cheng;  Zhao, Zheng;  Zhao, Peng;  Li, Xixiang;  Wang, Li;  Wang, Beilei;  Ye, Zi;  Wang, Jinhua;  Wang, Chu;  Zhang, Wei;  Gray, Nathanael S.;  Weisberg, Ellen L.;  Chen, Liang;  Liu, Jing;  Yun, Cai-Hong;  Liu, Qingsong
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Structural and biochemical studies of the PDGFRA kinase domain [期刊论文]
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2016-09-02, 卷号: 477, 期号: 4, 页码: 667-672
Liang, Ling;  Yan, Xiao-E.;  Yin, Yuxin;  Yun, Cai-Hong
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孤独症谱系障碍与胃肠道疾病研究进展 [期刊论文]
生理科学进展, 2016-08-25, 期号: 04, 页码: 300-304
张梦想;  王娟
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Exploiting aberrant mRNA expression in autism for gene discovery and diagnosis [期刊论文]
HUMAN GENETICS, 2016-07-01, 卷号: 135, 期号: 7, 页码: 797-811
Guan, Jinting;  Yang, Ence;  Yang, Jizhou;  Zeng, Yong;  Ji, Guoli;  Cai, James J.
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