学科主题临床医学
The 10/66 Dementia Research Group′s fully operationalised DSM-IV dementia computerized diagnostic algorithm, compared with the 10/66 dementia algorithm and a clinician diagnosis: a population validation study
Prince, Martin J.1; de Rodriguez, Juan Llibre2; Noriega, L.3; Lopez, A.4; Acosta, Daisy5; Albanese, Emiliano1; Arizaga, Raul6; Copeland, John R. M.7; Dewey, Michael1; Ferri, Cleusa P.1; Guerra, Mariella8; Huang, Yueqin9; Jacob, K. S.10; Krishnamoorthy, E. S.11; McKeigue, Paul12; Sousa, Renata13; Stewart, Robert J.14; Salas, Aquiles15; Sosa, Ana Luisa; Uwakwa, Richard; 10-66 Dementia Res Grp
刊名BMC PUBLIC HEALTH
2008-06-24
DOI10.1186/1471-2458-8-219
8
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Public, Environmental & Occupational Health
研究领域[WOS]Public, Environmental & Occupational Health
关键词[WOS]PREVALENCE ; VALIDITY ; CRITERIA ; AGECAT
英文摘要

Background: The criterion for dementia implicit in DSM-IV is widely used in research but not fully operationalised. The 10/66 Dementia Research Group sought to do this using assessments from their one phase dementia diagnostic research interview, and to validate the resulting algorithm in a population-based study in Cuba.

Methods: The criterion was operationalised as a computerised algorithm, applying clinical principles, based upon the 10/66 cognitive tests, clinical interview and informant reports; the Community Screening Instrument for Dementia, the CERAD 10 word list learning and animal naming tests, the Geriatric Mental State, and the History and Aetiology Schedule - Dementia Diagnosis and Subtype. This was validated in Cuba against a local clinician DSM-IV diagnosis and the 10/66 dementia diagnosis (originally calibrated probabilistically against clinician DSM-IV diagnoses in the 10/66 pilot study).

Results: The DSM-IV sub-criteria were plausibly distributed among clinically diagnosed dementia cases and controls. The clinician diagnoses agreed better with 10/66 dementia diagnosis than with the more conservative computerized DSM-IV algorithm. The DSM-IV algorithm was particularly likely to miss less severe dementia cases. Those with a 10/66 dementia diagnosis who did not meet the DSM-IV criterion were less cognitively and functionally impaired compared with the DSMIV confirmed cases, but still grossly impaired compared with those free of dementia.

Conclusion: The DSM-IV criterion, strictly applied, defines a narrow category of unambiguous dementia characterized by marked impairment. It may be specific but incompletely sensitive to clinically relevant cases. The 10/66 dementia diagnosis defines a broader category that may be more sensitive, identifying genuine cases beyond those defined by our DSM-IV algorithm, with relevance to the estimation of the population burden of this disorder.

语种英语
WOS记录号WOS:000257802300001
引用统计
被引频次:65[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/124393
专题医学人文研究院/公共教学部_北京大学临床心理中心
作者单位1.Med Univ Havana, Fac Med Finley Albarran, Havana, Cuba
2.Univ Policlin 19 Abril, Havana, Cuba
3.Community Mental Hlth Ctr, Havana, Cuba
4.UNPHU, Dept Internal Med, Geriatr Sect, Santo Domingo, Dominican Rep
5.Univ Liverpool, Hoylake Wirral CH47 1HW, England
6.Kings Coll London, Hlth Serv Res, Epidemiol Sect, London SE5 8AF, England
7.Neurol Fdn, Neuraxis Inst, Behav & Cognit Neurol Unit, Buenos Aires, DF, Argentina
8.Corpac SAN ISIDRO, Natl Inst Mental Hlth Honorio Delgado Hideyo Nogu, Psychogeriatr Unit, Dept 401, Lima, Peru
9.Peking Univ, Inst Mental Health, Beijing 100083, Peoples R China
10.Christian Med Coll & Hosp, Vellore 632004, Tamil Nadu, India
11.Srinivasan Ctr Clin Neurosci, Inst Neurol Sci, Voluntary Hlth Serv, Madras, Tamil Nadu, India
12.Univ Edinburgh, Human Genet Unit, MRC, Publ Hlth Sci Mol Med Ctr, Edinburgh EH8 9YL, Midlothian, Scotland
13.Cent Univ Venezuela, Fac Med, Caracas Univ Hosp, Dept Med, Caracas, Venezuela
14.Natl Inst Neurol & Neurosurg Mexico, Cognit & Behavior Unit, Mexico City 14269, DF, Mexico
15.Namdi Azikiwe Univ Teaching Hosp, Dept Mental Hlth, Nnewi, Anambra State, Nigeria
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GB/T 7714
Prince, Martin J.,de Rodriguez, Juan Llibre,Noriega, L.,et al. The 10/66 Dementia Research Group′s fully operationalised DSM-IV dementia computerized diagnostic algorithm, compared with the 10/66 dementia algorithm and a clinician diagnosis: a population validation study[J]. BMC PUBLIC HEALTH,2008,8.
APA Prince, Martin J..,de Rodriguez, Juan Llibre.,Noriega, L..,Lopez, A..,Acosta, Daisy.,...&10-66 Dementia Res Grp.(2008).The 10/66 Dementia Research Group′s fully operationalised DSM-IV dementia computerized diagnostic algorithm, compared with the 10/66 dementia algorithm and a clinician diagnosis: a population validation study.BMC PUBLIC HEALTH,8.
MLA Prince, Martin J.,et al."The 10/66 Dementia Research Group′s fully operationalised DSM-IV dementia computerized diagnostic algorithm, compared with the 10/66 dementia algorithm and a clinician diagnosis: a population validation study".BMC PUBLIC HEALTH 8(2008).
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