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Digit ratio (2D:4D) in Chinese women with gastric cancer
Wang, Lu1; Lu, Hong2; Li, Ke-Ke2; Bai, Chun-Yue2; Ma, Zhan-Bing2
通讯作者Lu, Hong(2)
刊名AMERICAN JOURNAL OF HUMAN BIOLOGY
2018-05-01
DOI10.1002/ajhb.23109
30期:3
收录类别SCI ; SSCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Anthropology ; Biology
研究领域[WOS]Anthropology ; Life Sciences & Biomedicine - Other Topics
英文摘要

ObjectivesDigit ratio, especially the second-to-fourth digit ratio (2D:4D), is a proxy indicator for prenatal exposure and sensitivity to sexual hormones which may influence the susceptibility to certain cancers. The aim of the present study was to investigate whether there is a possible association between 2D:4D and gastric cancer (GCA) in north Chinese women.

MethodsPhotographs of the left and right hands of 167 women (controls: 113; patients: 54) were collected. Left hand, right hand, and right minus left hand (Dr-l) 2D:4D were analyzed and compared.

ResultsThe GCA group presented significantly lower 2D:4D than controls (left: P<.01; right: P<.05). No significant difference was observed in Dr-l between the two groups. In patients, there were no correlations between 2D:4D and age at GCA or tumor staging.

ConclusionsDecreased 2D:4D (especially of the left hand) may suggest a higher prenatal testosterone (lower prenatal estrogen) exposure in north Chinese women with GCA.

语种英语
WOS记录号WOS:000434040300016
通讯作者邮箱chuan773@126.com
第一作者单位Peking Univ, Hlth Sci Ctr, Beijing 100191, Peoples R China
通讯作者单位Ningxia Med Univ, Key Lab Fertil Preservat & Maintenance, Key Lab Reprod & Genet Basic Med Sci, Minist Educ,Dept Med Genet & Cell Biol, Yinchuan 750004, Peoples R China
ISSN1042-0533
引用统计
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/141374
专题北京大学护理学院_护理学院
作者单位1.Ningxia Med Univ, Key Lab Fertil Preservat & Maintenance, Key Lab Reprod & Genet Basic Med Sci, Minist Educ,Dept Med Genet & Cell Biol, Yinchuan 750004, Peoples R China;
2.Peking Univ, Hlth Sci Ctr, Beijing 100191, Peoples R China
推荐引用方式
GB/T 7714
Wang, Lu,Lu, Hong,Li, Ke-Ke,et al. Digit ratio (2D:4D) in Chinese women with gastric cancer[J]. AMERICAN JOURNAL OF HUMAN BIOLOGY,2018,30(3).
APA Wang, Lu,Lu, Hong,Li, Ke-Ke,Bai, Chun-Yue,&Ma, Zhan-Bing.(2018).Digit ratio (2D:4D) in Chinese women with gastric cancer.AMERICAN JOURNAL OF HUMAN BIOLOGY,30(3).
MLA Wang, Lu,et al."Digit ratio (2D:4D) in Chinese women with gastric cancer".AMERICAN JOURNAL OF HUMAN BIOLOGY 30.3(2018).
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