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学科主题临床医学
Androgen Excess- Polycystic Ovary Syndrome Society: position statement on depression, anxiety, quality of life, and eating disorders in polycystic ovary syndrome
Dokras, Anuja1; Stener-Victorin, Elisabeth2; Yildiz, Bulent O.3; Li, Rong4; Ottey, Sasha5; Shah, Duru6; Epperson, Neill1,7; Teede, Helena8,9
通讯作者Dokras, Anuja(1)
关键词PCOS depression anxiety disordered eating quality of life
刊名FERTILITY AND STERILITY
2018-05-01
DOI10.1016/j.fertnstert.2018.01.038
109期:5页:888-899
收录类别SCI ; SSCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Obstetrics & Gynecology ; Reproductive Biology
研究领域[WOS]Obstetrics & Gynecology ; Reproductive Biology
关键词[WOS]RANDOMIZED CONTROLLED-TRIAL ; CLINICAL-PRACTICE GUIDELINE ; SYMPATHETIC-NERVE ACTIVITY ; 15-YEAR FOLLOW-UP ; BODY-MASS INDEX ; INCREASED RISK ; EMOTIONAL DISTRESS ; GENDER-DIFFERENCES ; PHYSICAL-EXERCISE ; MAJOR DEPRESSION
英文摘要

Objective: To formulate clinical consensus recommendations for screening depression, anxiety, health-related quality of life (HRQoL), and disordered eating symptoms in women with polycystic ovary syndrome (PCOS) and review prevalence based on phenotypes and ethnicity, changes over time, etiology, and impact of treatment.

Design: Systematic reviews and preparation of position statement.

Setting: Not applicable.

Patient(s): Women with PCOS and controls screened using validated tools.

Intervention(s): None.

Main Outcome Measure(s): Depressive symptoms, anxiety symptoms, disordered eating, and HRQoL scores.

Result(s): Several studies demonstrate that women with PCOS have an increased prevalence of higher depression and anxiety scores and higher odds of moderate and severe depressive and anxiety symptoms compared with controls. Obesity, hyperandrogenism, and fertility have a weak association with these symptoms. HRQoL scores are consistently reduced in PCOS, with infertility and weight concerns having the most significant impact. Some studies suggest an increased prevalence of disordered eating in women with PCOS compared with controls. The few studies that have evaluated the impact of PCOS-related treatments (lifestyle interventions and pharmacotherapy) show no detrimental effect or some improvement in depressive and anxiety symptoms and HRQoL scores.

Conclusion(s): In women with PCOS, screening for depressive and anxiety symptoms should be offered at the time of diagnosis and screening for disordered eating should be considered. Further research is required across PCOS phenotypes, in longitudinal cohorts and on impact of therapy on depressive and anxiety syptoms, HRQOL, and disordered eating. (C) 2018 by American Society for Reproductive Medicine.

语种英语
WOS记录号WOS:000432453200033
通讯作者邮箱adokras@obgyn.upenn.edu
第一作者单位Univ Penn, Dept Obstet & Gynecol, Philadelphia, PA 19104 USA
通讯作者单位Univ Penn, Dept Obstet & Gynecol, Philadelphia, PA 19104 USA
ISSN0015-0282
引用统计
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/141884
专题北京大学第三临床医学院_生殖医学中心
作者单位1.Univ Penn, Dept Obstet & Gynecol, Philadelphia, PA 19104 USA;
2.Karolinska Inst, Dept Physiol & Pharmacol, Stockholm, Sweden;
3.Hacettepe Univ, Sch Med, Dept Internal Med, Div Endocrinol & Metab, Ankara, Turkey;
4.Peking Univ, Hosp 3, Reprod Med Ctr, Dept Obstet & Gyneocol, Beijing, Peoples R China;
5.PCOS Challenge, Atlanta, GA USA;
6.Gynaecworld, Bombay, Maharashtra, India;
7.Univ Penn, Dept Psychiat, Perelman Sch Med, Philadelphia, PA 19104 USA;
8.Monash Univ, Sch Publ Hlth & Prevent Med, Monash Ctr Hlth Res & Implementat, Clayton, Vic, Australia;
9.Monash Hlth, Clayton, Vic, Australia
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GB/T 7714
Dokras, Anuja,Stener-Victorin, Elisabeth,Yildiz, Bulent O.,et al. Androgen Excess- Polycystic Ovary Syndrome Society: position statement on depression, anxiety, quality of life, and eating disorders in polycystic ovary syndrome[J]. FERTILITY AND STERILITY,2018,109(5):888-899.
APA Dokras, Anuja.,Stener-Victorin, Elisabeth.,Yildiz, Bulent O..,Li, Rong.,Ottey, Sasha.,...&Teede, Helena.(2018).Androgen Excess- Polycystic Ovary Syndrome Society: position statement on depression, anxiety, quality of life, and eating disorders in polycystic ovary syndrome.FERTILITY AND STERILITY,109(5),888-899.
MLA Dokras, Anuja,et al."Androgen Excess- Polycystic Ovary Syndrome Society: position statement on depression, anxiety, quality of life, and eating disorders in polycystic ovary syndrome".FERTILITY AND STERILITY 109.5(2018):888-899.
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