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学科主题临床医学
Time-Dependent Changes in the Magnetic Resonance Detection of Brain Metastases Using Single-Dose Gadobutrol
Fan, Bing1,2; Li, Mei-jiao2; Wang, Xiao-ying2; Xu, Yu-feng2; Li, Fei-yu2; Zhang, Lai-yun2; Jiang, Jian1; Jiang, Yan-yan2
通讯作者Wang, Xiao-ying(2)
关键词Gadobutrol Magnetic Resonance Imaging Brain Metastases Delay Time
刊名IRANIAN JOURNAL OF RADIOLOGY
2018
DOI10.5812/iranjradiol.66054
15期:1
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Radiology, Nuclear Medicine & Medical Imaging
研究领域[WOS]Radiology, Nuclear Medicine & Medical Imaging
关键词[WOS]CENTRAL-NERVOUS-SYSTEM ; 3 T ; CONTRAST ; MULTICENTER ; MRI ; MODEL ; GADOTERIDOL ; EFFICACY ; TARGET ; SAFETY
英文摘要

Objectives: The effect of delay in imaging on the assessment of contrast-enhanced magnetic resonance imaging (CE-MRI) has not been extensively studied. This study evaluated the effect of different delay times (3, 7, and 10 minutes) on gadobutrol (Gadovist)enhanced MRI for diagnosis of brain metastases.

Patients and Methods: This single-center, blind-reading, post-marketing study enrolled 52 patients with suspected or known brain metastases who received gadolinium-enhanced MR examinations. All the patients received 0.1 mmol/kg dose of gadobutrol, and serial axial T1 FLAIR images were obtained at each MR examination after a delay of 3, 7, and 10 minutes. The images were evaluated by two experienced radiologists independently. The evaluation included subjective and objective evaluations of the image quality.

Results: Thirty-four patients were diagnosed with brain metastases. There were 295, 301, and 301 lesions detected in the 3, 7, and 10 minutes delay groups, respectively. Subjective evaluation revealed a higher mean quality score of lesion edge, lesion interior, and overall image quality in the 7 and 10 minutes groups compared to the 3 minutes group. Images in the 7- or 10-min delay groups had significantly greater CNR and CBR than the 3-min group (P < 0.05).

Conclusion: A delay time of 7 minutes was considered optimal for imaging after gadobutrol administration in patients with brain metastases.

语种英语
WOS记录号WOS:000434463200026
通讯作者邮箱cjr.wangxiaoying@vip.163.com
第一作者单位Yichang Yiling Hosp, Dept Radiol, Yichang, Peoples R China ; Peking Univ, Hosp 1, Dept Radiol, Beijing 100034, Peoples R China
通讯作者单位Peking Univ, Hosp 1, Dept Radiol, Beijing 100034, Peoples R China
ISSN1735-1065
引用统计
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/142269
专题北京大学第一临床医学院_放射治疗科
北京大学第一临床医学院_医学影像科
北京大学第三临床医学院_放射科
作者单位1.Yichang Yiling Hosp, Dept Radiol, Yichang, Peoples R China;
2.Peking Univ, Hosp 1, Dept Radiol, Beijing 100034, Peoples R China
推荐引用方式
GB/T 7714
Fan, Bing,Li, Mei-jiao,Wang, Xiao-ying,et al. Time-Dependent Changes in the Magnetic Resonance Detection of Brain Metastases Using Single-Dose Gadobutrol[J]. IRANIAN JOURNAL OF RADIOLOGY,2018,15(1).
APA Fan, Bing.,Li, Mei-jiao.,Wang, Xiao-ying.,Xu, Yu-feng.,Li, Fei-yu.,...&Jiang, Yan-yan.(2018).Time-Dependent Changes in the Magnetic Resonance Detection of Brain Metastases Using Single-Dose Gadobutrol.IRANIAN JOURNAL OF RADIOLOGY,15(1).
MLA Fan, Bing,et al."Time-Dependent Changes in the Magnetic Resonance Detection of Brain Metastases Using Single-Dose Gadobutrol".IRANIAN JOURNAL OF RADIOLOGY 15.1(2018).
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