IR@PKUHSC  > 北京大学第三临床医学院  > 心血管内科
学科主题临床医学
Psychological Status of Volunteers in a Phase I Clinical Trial Assessed by Symptom Checklist 90 (SCL-90) and Eysenck Personality Questionnaire (EPQ)
Wei, Yudong1; Li, Haiyan1,2; Wang, Huali3; Zhang, Shuang1; Sun, Yumei4
通讯作者Wei, Yudong(1) ; Sun, Yumei(4)
关键词Adaptation, Psychological Clinical Trial, Phase I Questionnaires
刊名MEDICAL SCIENCE MONITOR
2018-07-17
DOI10.12659/MSM.909524
24页:4968-4973
收录类别SCI ; SSCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Medicine, Research & Experimental
研究领域[WOS]Research & Experimental Medicine
英文摘要

Background: The psychological status of volunteers was investigated to provide a theoretical method for Phase I clinical trial management and result analysis.

Material/Methods: The Symptom Checklist 90 (SCL-90) and Eysenck Personality Questionnaire (EPQ) were used to assess the psychological status 200 healthy Chinese volunteers.

Results: SCL-90 results indicate that the average value of positive factors is 10.32 +/- 14.26 by self-assessment of healthy volunteers, somatization factor is 1.13 +/- 0.13, compulsive symptom factor is 1.29 +/- 0.27, interpersonal sensitivity factor is 1.31 +/- 0.21, depression factor is 1.26 +/- 0.33, anxiety factor is 1.21 +/- 0.21, hostility factor is 1.08 +/- 0.26, phobia factor is 1.05 +/- 0.18, paranoid factor is 1.12 +/- 0.23, and psychotic symptom factor is 1.17 +/- 0.26.

Conclusion: Compared to the norm in China, the score of each factor of healthy volunteers was relatively low, with a statistically significant difference (P<0.001). EPQ results show that P score was 4.59 +/- 2.33, E score is 13.13 +/- 4.32, N score was 6.89 +/- 5.26, and L score was 13.21 +/- 4.25 for the 200 healthy volunteers. Compared to the norm in China, the P and N scores were lower, and the E and L scores were higher, with a statistically significant difference (P<0.001).

语种英语
WOS记录号WOS:000439533800002
通讯作者邮箱weiyudong@bjmu.edu.cn ; sym8022@bjmu.edu.cn
第一作者单位Peking Univ, Hosp 3, Drug Clin Trial Ctr, Beijing, Peoples R China
通讯作者单位Peking Univ, Sch Nursing, Beijing, Peoples R China ; Peking Univ, Hosp 3, Drug Clin Trial Ctr, Beijing, Peoples R China
ISSN1643-3750
引用统计
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/142460
专题北京大学第三临床医学院_心血管内科
北京大学护理学院_护理学院
北京大学精神卫生研究所_精神科
作者单位1.Peking Univ, Hosp 3, Dept Cardiol, Beijing, Peoples R China;
2.Peking Univ, Sch Nursing, Beijing, Peoples R China;
3.Peking Univ, Hosp 3, Drug Clin Trial Ctr, Beijing, Peoples R China;
4.Peking Univ, Hosp 6, Inst Mental Hlth, Beijing, Peoples R China
推荐引用方式
GB/T 7714
Wei, Yudong,Li, Haiyan,Wang, Huali,et al. Psychological Status of Volunteers in a Phase I Clinical Trial Assessed by Symptom Checklist 90 (SCL-90) and Eysenck Personality Questionnaire (EPQ)[J]. MEDICAL SCIENCE MONITOR,2018,24:4968-4973.
APA Wei, Yudong,Li, Haiyan,Wang, Huali,Zhang, Shuang,&Sun, Yumei.(2018).Psychological Status of Volunteers in a Phase I Clinical Trial Assessed by Symptom Checklist 90 (SCL-90) and Eysenck Personality Questionnaire (EPQ).MEDICAL SCIENCE MONITOR,24,4968-4973.
MLA Wei, Yudong,et al."Psychological Status of Volunteers in a Phase I Clinical Trial Assessed by Symptom Checklist 90 (SCL-90) and Eysenck Personality Questionnaire (EPQ)".MEDICAL SCIENCE MONITOR 24(2018):4968-4973.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Wei, Yudong]的文章
[Li, Haiyan]的文章
[Wang, Huali]的文章
百度学术
百度学术中相似的文章
[Wei, Yudong]的文章
[Li, Haiyan]的文章
[Wang, Huali]的文章
必应学术
必应学术中相似的文章
[Wei, Yudong]的文章
[Li, Haiyan]的文章
[Wang, Huali]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。