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学科主题: 神经病学
题名:
早期吉兰-巴雷综合征的神经电生理特点分析
其他题名: Electrophysiological characteristics in patients with early Guillain-Barré syndrome
作者: 潘涛; 贾志荣; 王亭亭; 王洪霞; 石昕; 梁为
关键词: 格林· ; 巴利综合征 ; 电生理学 ; H反射 ; 神经传导 ; Guillain-Barré ; syndrome ; Electrophysiology ; H-reflex ; Neural conduction
刊名: 中华神经科杂志
发表日期: 2011
DOI: 10.3760/cma.j.issn.1006-7876.2011.11.003
卷: 44, 期:11, 页:735-738
收录类别: 中国科技核心期刊 ; CSCD
文章类型: Journal Article
摘要: 目的 分析发病4周内吉兰-巴雷综合征(GBS)患者的F波、H反射及神经传导的改变特点,探讨F波及H反射检查在早期GBS中的诊断价值.方法 回顾性分析我院40例确诊GBS患者的神经电生理资料特点,依据病程分为2组(≤2周组及>2周组).使用卡方检验,分别对两组患者的F波、H反射、运动神经传导速度(MCV)和感觉神经传导速度(SCV)检测的异常率进行分析.结果 病程≤2周组及>2周组F波异常比例分别为17/20、7/18,H反射的异常比例分别为13/20、12/19,MCV异常率为28.4%(25/88)、32.9%(26/79),运动神经传导远端潜伏期异常率为40.9%(36/88)、36.7%(29/79),复合肌肉动作电位波幅异常率为35.2%(31/88)、32.9%(26/79),SCV异常率为11.2%(10/89)、25.2%(24/95).两组患者中F波、H反射异常率均较高,且两组间F波异常比例(X2 =8.657,P=0.003)及SCV异常率(x2 =6.002,P=0.014)差异具有统计学意义.结论 F波及H反射对GBS的早期诊断具有一定的诊断参考价值;神经电生理检查对GBS具有重要诊断价值. Objective To analyze the characteristics of the F waves,H-reflex and nerve conductions and its diagnostic value in the patients with Guillain-Barré syndrome(GBS)onset within 4 weeks.Methods The electrophysiological data of the 40 patients with GBS were analyzed retrospectively.These patients were divided into 2 groups according to the duration of illness including in 2 week' s group and over 2 week' s group.The results of the F waves,H-reflex,the motor nerve conduction velocity (MCV),and the sensory nerve conduction velocity(SCV)of these patients were analyzed.Results The abnormality rate of the F waves was 17/20 and 7/18 respectively in less 2 week' s group and over 2 week' s.The H-reflexes were 13/20 and 12/19.The MCV was 28.4%(25/88)and 32.9%(26/79).The distal motor latency was 40.9%(36/88)and 36.7%(29/79).The compound muscle action potential amplitude was 35.2%(31/88)and 32.9%(26/79)respectively in these two groups.The abnormality rate of the SCV was 11.2%(10/89)and 25.2%(24/95)respectively in the two groups.The higher abnormality rate of these tests was the F waves and H-reflex in both the groups.The abnormality rates of the F waves(x2 =8.657,P =0.003)and SCV(x2 =6.002,P =0.014)were significantly different between the two groups.There were no significant differences in the other tests.Conclusion The electrophysiological tests are valuable in the diagnosis of GBS.The F waves and H-reflex are more significant for early diagnosis of GBS.
语种: 中文
原文出处: 查看原文
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内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/41175
Appears in Collections:北京大学第一临床医学院_神经内科_期刊论文

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作者单位: 100034,北京大学第一医院神经内科
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