北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 北京大学第一临床医学院  > 神经内科  > 期刊论文
学科主题: 神经病学
题名:
帕金森病的眼球跟踪运动特点
其他题名: Tracing eyeball movements in Parkinson' s disease
作者: 唐澍; 赵桂萍; 赵玉宾; 孙相如
关键词: 眼球运动 ; 帕金森病 ; 眼震电图描记术 ; Eye movements ; Parkinson disease ; Electronystagmography
刊名: 中华神经科杂志
发表日期: 2009
DOI: 10.3760/cma.j.issn.1006-7876.2009.01.013
卷: 42, 期:1, 页:46-49
收录类别: 中国科技核心期刊 ; CSCD
文章类型: Journal Article
摘要: 目的 定量分析帕金森病(PD)患者眼球跟踪运动的特点,为评价PD患者的前庭功能提供依据.方法 选取30名健康人(对照组)和55例PD患者(PD组)作为受试者,PD组包括静止件震颤起病者31例(静止性震颤组),运动减少起病者23例(运动减少组),混合起病1例.对全部受试者进行眼震电图检杳.比较PD组和对照组跟踪运动增益值(gain,G)的差异,运动减少组和静止性震颤组跟踪运动的差异,PD患者双侧跟踪运动的非对称性和健康对照者的差异.结果 PD患者双侧跟踪运动的增益值(G左:0.79±0.10、G右:0.78±0.11)较对照组(G左:0.86±0.05、G右:0.85±0.06)明显降低(U=394.500、t=3.547,均P<0.01),运动减少组(G左:0.79±0.14、G右:0.75±0.14)与静止性震颤组(G左:0.79±0.06、G右:0.81±0.07)眼球跟踪运动增益值差异无统计学意义(t=-0.100、2.005,均P0.05).病例组左右两侧的跟踪运动非对称性(1.03±0.97)明显大于对照组(0.87±0.86,U=755.500,P<0.05).结论 PD患者眼球跟踪运动速度明显减慢,但不存在类型间的差异,两侧跟踪运动存在不对称性. Objective To evaluate the eyeball movement examination on Parkinson' s disease (PD) and investigate their vestibular function.Methods Thirty healthy volunteers and 55 PD patients served as subjects.Thirty-one patients had bradykinesia, 23 patients had resting tremor at first visit and 1 had both.Electronystagmogram examinations were performed in all the subjects.The eyeball movment gain (G) of PD group was compared with controls and the difference between the bradykinesia group and resting tremor group was analyzed.Dissymmetry of the bilateral pursuit movement was investigated.Results The eyeball movement gains decreased in PD patients (Left G 0.79±0.10, Right G 0.78±0.11) significantly (U = 394.500, t = 3.547, P < 0.01) compared with controls (Left G 0.86±0.05, Right G 0.85±0.06).There was no difference (t = -0.100,2.005, P 0.05) between the bradykinesia group (Left G 0.79± 0.14,Right G 0.74±0.14) and the resting tremor group ( Left G 0.79±0.06,Right G 0.81±0.07).The dissymmetry of the bilateral movement increased significantly (U = 755.500, P < 0.05) in PD group (1.03±0.97) than in controls (0.87±0.86).Conclusion The velocity of the eyeball movement has decreased in patients with PD.There is no difference of the pursuit gain between bradykinesia group and the resting tremor group.The bilateral vestibular function is involved dissymmetrically.
语种: 中文
原文出处: 查看原文
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/41252
Appears in Collections:北京大学第一临床医学院_神经内科_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: 北京大学第一医院神经内科,100034
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[唐澍]'s Articles
[赵桂萍]'s Articles
[赵玉宾]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[唐澍]‘s Articles
[赵桂萍]‘s Articles
[赵玉宾]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace