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学科主题: 放射医学
题名:
不同影像方法评价乳腺密度的一致性研究
其他题名: Quantitative assessment of breast density: comparison of different methods
作者: 秦乃姗1; 郭丽1; 党易1; 宋鲁新1; 王霄英1
关键词: 乳房 ; 乳房X线摄影术 ; 磁共振成像 ; 图像处理,计算机辅助 ; Breast ; Mammography ; Magnetic resonance imaging ; Image processing,computer-assisted
刊名: 中华放射学杂志
发表日期: 2011
DOI: 10.3760/cma.j.issn.1005-1201.2011.03.012
卷: 45, 期:3, 页:284-287
收录类别: 中国科技核心期刊 ; 中文核心期刊 ; CSCD
文章类型: Journal Article
摘要: 目的 比较不同影像学方法评价乳腺密度的一致性.方法 搜集行DR及乳腺MR检查的患者共60例(两项检查间隔时间小于1个月).乳腺DR采集的原始图像经R2 工作站软件处理,计算机自动计算出乳房体积、乳腺实质体积及乳腺密度.乳腺X线片由2名X线影像诊断医师独立阅读,根据常用的乳腺实质分型方法(Wolfe分型、ACR分型)对58例乳腺实质进行分类.乳腺MR图像由2名影像医师通过模糊C聚类方法计算乳腺实质和脂肪的像素比例,得到乳腺密度.2周后,参与研究的其中1名影像医师重复上述工作.采用一致性检验评价各种测量方法观察者内、观察者间及不同测量方法间的一致性.结果 Wolfe分型观察者内和观察者间一致性分别为0.74、0.65;ACR分型观察者内和观察者间一致性分别为0.74、0.82;Wolfe分型与ACR分型两者间一致性为0.77;MRI得到的乳腺密度观察者内和观察者间一致性分别为0.98和0.96;MRI与X线摄影计算机自动获取的乳腺密度具有较好的一致性(r=0.81,P<0.01).结论 乳腺DR和MR两种方法测量得到的乳腺密度具有较高的一致性,可通过R2工作站对乳腺密度进行评价. Objective To Compare different methods of quantitative breast density measurement.Methods The study included sixty patients who underwent both mammography and breast MRI. The breast density was computed automatically on digital mammograms with R2 workstation. Two experienced radiologists read the mammograms and assessed the breast density with Wolfe and ACR classification respectively. Fuzzy C-means clustering algorithm (FCM) was used to assess breast density on MRI. Each assessment method was repeated after 2 weeks. Spearman and Pearson correlations of inter- and intrareader and intermodality were computed for density estimates. Results Inter- and intrareader correlation of Wolfe classification were 0. 74 and 0. 65, and they were 0. 74 and 0. 82 for ACR classification respectively.Correlation between Wolfe and ACR classification was 0. 77. High interreader correlation of 0. 98 and intrareader correlation of 0. 96 was observed with MR FCM measurement. And the correlation between digital mammograms and MRI was high in the assessment of breast density (r = 0. 81, P < 0. 01). Conclusion High correlation of breast density estimates on digital mammograms and MRI FCM suggested the former could be used as a simple and accurate method.
语种: 中文
原文出处: 查看原文
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内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/42188
Appears in Collections:北京大学第一临床医学院_放射治疗科_期刊论文

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作者单位: 1.北京大学第一医院放射科,100034
2.北京大学生物医学工程功能成像中心,前沿交叉学科研究院
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