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IR@PKUHSC  > 北京大学第一临床医学院  > 放射治疗科  > 期刊论文
学科主题: 放射医学
题名:
扩散加权成像鉴别兔炎性及转移性淋巴结肿大的实验研究
其他题名: Experiment study on MR diffusion weighted imaging in rabbit models of lymphadenopathy:comparison between inflammatory and metastatic lymph node
作者: 吴冰; 刘婧; 王霄英
关键词: 淋巴结 ; 磁共振成像,弥散 ; 模型,动物 ; Lvmph nodes: D !E imaing: Models.animal
刊名: 中华放射学杂志
发表日期: 2009
DOI: 10.3760/cma.j.issn.1005-1201.2009.07.023
卷: 43, 期:7, 页:759-761
收录类别: 中国科技核心期刊 ; 中文核心期刊 ; CSCD
文章类型: Journal Article
摘要: 目的 探讨DWI鉴别兔良、恶性淋巴结肿大的价值.方法 对18只炎性增生性兔淋巴结(34个)肿大模型和9只肿瘤转移性兔淋巴结(18个)肿大模型进行常规MR和DWI检查,并采用独立样本t检验比较2组淋巴结短径和ADC值的差异.结果 对34个炎性增生型淋巴结和18个肿瘤转移性淋巴结进行了观察,炎性组和转移组淋巴结的短径分别为(8.14±2.79)和(6.29±1.48)mm,差异无统计学意义(t=2.624,P>0.05).炎症组和转移组淋巴结的ADC值分别为(1.19±0.31)×10-3和(1.31±0.27)×10-3mm2/s,差异无统计学意义(t=1.449,P>0.05).结论 DWI可显示肿大的淋巴结,但其ADC值差异不大,不足以作为比较并鉴别淋巴结良恶性的手段. Objective To investigate the value of MR DWI in comparing inflammatory with metastastic lymph node in animal models of lymph disease.Methods Eighteen rabbits with benign lymphadenopathy and 9 rabbits with malignant lymphadenopathy underwent routine MRI and DWI examination.Independent-samples t test was used to compare the sizes and apparent diffusion coefficient (ADC) values between the two groups.Results Thirty-four inflammatory lymph nodes and 18 metastastic lymph nodes were observed .The size of lymph nodes was (8.14±2.79) and (6.29±1.48) mm in the benign and malignant groups, respectively.There was no significant statistical difference between the sizes of the two groups (t=2.624, P 0.05).Mean ADC value of lymph nodes was (1.19±0.31)×10-3mm2/s and (1.31±0.27)×10-3mm2/s in the benign and malignant groups, respectively.There was no significant statistical difference between the ADC values of benign and malignant lymph nodes (t=1.449,P 0.05).Conclusion DWI sequence can be used to show lymphadenopathy, but the ADC value is insufficient to differentiate benign lymph nodes from malignant lymphadenopathy.
语种: 中文
原文出处: 查看原文
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内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/42248
Appears in Collections:北京大学第一临床医学院_放射治疗科_期刊论文

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作者单位: 北京大学第一医院放射科北京大学前沿交叉学科研究院功能成像研究中心,100034
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