北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 北京大学第一临床医学院  > 医学影像科  > 期刊论文
学科主题: 影像医学
题名:
儿童白质消融性脑白质病的MRI表现
其他题名: MRI findings in children with vanishing white matter disease
作者: 胡建敏1; 张海华1; 肖江喜1; 吴晔1; 谢晟1; 王静敏1
关键词: 脑白质病,进行性多灶性 ; 磁共振成像 ; Leukoencephalopathy,progressive multifocal ; Magnetic resonance imaging
刊名: 中华放射学杂志
发表日期: 2013
DOI: 10.3760/cma.j.issn.1005-1201.2013.10.009
卷: 47, 期:10, 页:908-911
收录类别: 中国科技核心期刊 ; 中文核心期刊 ; CSCD
文章类型: Journal Article
摘要: 目的 探讨白质消融性脑白质病(VWM)的MRI特征表现.方法 回顾性分析2008年至2013年间经本院儿科基因确诊为VWM的10例患儿的临床及MR资料.由2名资深的神经放射医师进行阅片,对白质病变部位(大脑、小脑、脑干、胼胝体及内外囊)、范围、信号特点、有无囊变、脑萎缩及基底节受累等进行分析.结果 10例大脑中央白质均弥漫受累,9例部分皮层下白质受累,7例伴U形纤维受累;7例伴有囊变;8例内囊后肢受累,7例外囊受累,8例胼胝体内缘(透明隔缘)受累.2例丘脑和苍白球出现异常信号,6例脑干白质受累,7例小脑白质受累.结论 大脑中央白质出现弥漫对称的异常信号伴囊变是VWM特征性的MRI表现,对该病的诊断具有重要价值. Objective To describe the MRI features of vanishing white matter disease (VWM).Methods Ten patients diagnosed as VWM between 2008-2013 were enrolled,with the mean age of(40 ±23)months.The clinical materials and MR images of them were reviewed retrospectively.The findings of MRI were analyzed by two experienced neuroradiologists in this study,including the location (cerebrum,cerebellum,brainstem,corpus callosum and internal/external capsule),size and signal intensity of the lesions,as well as the presence of cystic degeneration,cerebrum atrophy and the abnormal signal of the basal nuclei.Results MRI of brain typically showed extensive abnormal signal in the cerebral central white matter (10/10) and the focal lesion in subcortical white matter (9/10).The involvement of U-fibers was present in 7 cases.Cystic degeneration of the affected white matter was found in 7 cases.Abnormal signal also appeared in the white matter of posterior limb of the internal capsule (8/10),the external capsule (7/10),the inner rim (the callosal-septal interface) of the corpus callosum (8/10).The lesions of the thalamus and globus pallidus were detected in 2 cases.The white matter of the brainstem and cerebellum were involved in 6 and 7 cases respectively.Conclusion VWM typically shows a diffuse and symmetrical abnormal signal in the cerebral white matter with cystic degeneration on MRI,which is usually diagnostic.
语种: 中文
原文出处: 查看原文
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/42610
Appears in Collections:北京大学第一临床医学院_医学影像科_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: 1.100034,北京大学第一医院医学影像科
2.100034,北京大学第一医院儿科
3.中日友好医院放射科
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[胡建敏]'s Articles
[张海华]'s Articles
[肖江喜]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[胡建敏]‘s Articles
[张海华]‘s Articles
[肖江喜]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace