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学科主题: 影像医学
题名:
100 kVp条件下碘克沙醇(270 mg I/mL)应用于分次团注双期CTU的可行性研究
其他题名: Feasibilitystudyofsplit-bolus2-phaseCTurographywithiodixanol(270mgI/mL)andtubevoltageas100kVp
作者: 王慧慧; 王鹤; 王霄英; 姜健; 高福生; 张保翠
关键词: 体层摄影术,X线计算机 ; 泌尿系成像 ; 对比剂 ; 迭代重建 ; 辐射量 ; 体型特异性剂量估计 ; Tomography,X-ray computed ; Urography ; Iterative reconstruction ; Radiation dose ; Size-specific dose estimate
刊名: 放射学实践
发表日期: 2014
期: 4, 页:373-377
收录类别: 中国科技核心期刊
文章类型: Journal Article
摘要: 目的:探讨100 kVp条件下、碘克沙醇(270 mg I/mL)应用于分次团注CT尿路成像(CTU)的可行性。方法:因血尿待查行CTU检查的连续10例患者行双期团注CTU扫描:管电压采用100 kVp,平扫后分2次团注对比剂碘克沙醇(270 mg I/mL),第一期剂量为0.6 mL/kg,延时10~15 min后行第二期团注,剂量为0.9 mL/kg,对比剂第2次开始注射后延时100 s行肾实质-肾盂期CTU扫描。使用滤波反投影(FBP)及30%、50%、80%和100%(间隔10%)自适应统计迭代重建(ASiR)算法共获得5组CTU图像。记录并计算CTU 的体型特异性剂量评估(SSDE)值及有效剂量(ED)。由两位阅片者对2种重建方法共5组图像进行盲法独立阅片,对图像质量进行主观评分。测量各组图像的噪声、尿路各段CT值及对比噪声比(CNR)。结果:本研究中平均对比剂碘摄入量为26.39gI/例。SSDE 为(15.38±3.34)mGy,ED 为(6.45±1.95)mSv。与FBP图像相比,30%~100% ASiR图像噪声逐渐降低,且差异具有高度统计学意义(P<0.001),但各组间多数尿路分段CNR的差异无统计学意义(P=0.005~1.000),80%ASiR相对于其它重建方法具有更高的图像质量主观评分。结论:100 kVp条件下、碘克沙醇(270 mg I/mL)应用于双期团注CTU,可获得符合临床诊断需要的图像,此种条件下推荐使用80%ASiR重建图像。 Objective:To evaluate the feasibility of split-bolus 2-phase CT urography (CTU)with Iodixanol (270mg I/mL) and 100kVp technique.Methods:Ten consecutive patients with hematuria undergone CTU were recruited in this study.Split bolus CTU using iodixanol (270mg I/mL)was performed,the tube voltage was 100kVp.After plain CT,Iodixanol was in-jected with dual bolus.The injection dose of first bolus was 0.6mL/kg,the contrast material of second bolus was injected af-ter 10~15min,the injection dose was 0.9mL/kg.The renal parenchymal-pelvic phase was taken 100s after the second injec-tion.5 sets of CTU images were obtained with filtered back projection (FBP)and 30%,50%,80% and 100% adaptive sta-tistical iterative reconstruction (ASiR).The size-specific dose estimate (SSDE)and effective dose (ED)were recorded and calculated.Scores were assigned by two qualified readers double-blindly to evaluate the image quality with different recon-struction algorithm.The CT values,image noise,and CNR of different segments of renal collection system were measured respectively.Results:The mean iodine intake of contrast material was 26.39g I per person.The mean radiation dose was (15.38±3.34)mGy for SSDE and (6.45±1.95)mSv for ED.Compared with FBP images,the image noise reduced gradual-ly from 30% to 100% ASiR,with statistic significance (P<0.001).No statistic significance was existed in the CNR of dif-ferent segments of collective system (P= 0.005~1.000).The subjective image quality score was the highest in 80%ASiR. Conclusion:Application of iodixanol (270mg I/mL)split-bolus 2-phase CTU using tube voltage as 100kVp can meet clinical need with good enough image quality,and 80%ASiR reconstruction is recommended.
语种: 中文
原文出处: 查看原文
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/42788
Appears in Collections:北京大学第一临床医学院_医学影像科_期刊论文

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作者单位: 北京大学第一医院医学影像科, 北京,100034
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