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学科主题: 影像医学
题名:
儿童线粒体脑肌病的MRI表现
其他题名: Mitochondrial Encephalomyopathy in Children: MRI Appearance
作者: 王霄英; 肖江喜; 蒋学祥; 周元春; 高玉洁
关键词: 线粒体脑肌病 ; 磁共振成像 ; 儿童
刊名: 中国医学影像技术
发表日期: 2001
DOI: 10.3321/j.issn:1003-3289.2001.04.008
卷: 17, 期:4, 页:314-316
收录类别: 中国科技核心期刊 ; 中文核心期刊 ; CSCD
文章类型: Journal Article
摘要: 目的回顾性研究20例线粒体脑肌病患儿的MRI表现。方法 20例证实为线粒体脑肌病的患儿,脑内均有MRI阳性表现,研究其MRI表现的类型。结果 20例患儿脑内病灶均表现为T1低、T2高信号,8例有不同程度的脑萎缩。18例主要为灰质受累,其中4例同时累及灰质和白质。2例主要为白质受累。结论儿童线粒体脑肌病的MRI表现是多样性的。当MRI表现为灰质异常信号、脑萎缩、不典型梗塞或白质病变且合并临床难以解释的多系统症状时,应考虑到该病的可能。 Objective We retrospectively studied 20 children with mitochondrial encephalomyopathy whose MRI examina tions demonstrated abnormalities. Methods MRI evaluations were done in 20 children with confirmed mitochondrial encepha lomyopathy proved by muscle biopsy and biochemical laboratory examinations. Results Different patterns of brain parenchy mal lesions were demonstrated, all lesions gave low signal on T1-weighted and high signal on T2-weighted images, in addition to brain atrophy of different degrees in 8 children.18 patients had involvement of gray matter, 4 of the patients showed deep gray matter abnormalities and cerebral infarction with involvement of cortex and subcortical white matter. 2 patients had exclu sively involvement of white matter, which were nonspecific white matter changes of the trigonal area. Conclusion Mitochon drial encephalomyopathy has a wide range of MRI findings. Although no one set of findings is diagnostic of the disease, the combination of gray matter especially deep gray matter involvement, brain atrophy, untypical infarction and involvement of pe ripheral white matter should suggest the diagnosis, especially when associated with a variety of neuromuscular symptoms.
语种: 中文
原文出处: 查看原文
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内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/42845
Appears in Collections:北京大学第一临床医学院_医学影像科_期刊论文

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作者单位: 北京大学第一医院医学影像科,
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