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学科主题: 影像医学
题名:
磁共振脑部侧支循环的灌注成像
其他题名: Cerebral collateral magnetic resonance imaging
作者: 吴冰1; 王霄英1; 郭佳1; 莫大鹏1; 谢晟1; Wong, Eric C1; 张珏1; 鲍圣德1; 黄一宁1; 蒋学祥1
关键词: 颈动脉狭窄 ; 侧支循环 ; 磁共振成像 ; Carotid stenosis ; Collateral circulation ; Magnetic resonance imaging
刊名: 中华神经科杂志
发表日期: 2009
DOI: 10.3760/cma.j.issn.1006-7876.2009.03.010
卷: 42, 期:3, 页:179-182
收录类别: 中国科技核心期刊 ; CSCD
文章类型: Journal Article
摘要: 目的 研究血管编码的动脉自旋标记(VE-ASL)灌注方法对于脑部侧支循环灌注的显示能力.方法 56例超声检查显示颈内动脉狭窄的患者入组.使用VE-ASL测量侧支循环的存在及功能.Willis环侧支循环的存在通过定义A1段和后交通动脉的血流状态确定.远端侧支循环灌注功能通过测量不同脑区脑血流量来区分:脑血流量≥10 ml·min-1100g-1为供血功能可以接受,脑血流量<10 ml·min-1·100g-1为供血不足.使用交叉表将VE-ASL得到的结果与MRA、DSA的结果进行比较.计算Kappa值比较不同方法之间的一致性.比较颈动脉支架患者在治疗前后VE-ASL结果的差异.结果 比较MRA和VE-ASL确定A1段和后交通血流状态的一致性,Kappa值分别为0.746及0.700.对于侧支循环灌注功能的区分,DSA与VE-ASL比较的Kappa值是0.914.除基于Willis环的侧支循环,VE-ASL还显示了通过软脑膜的侧支血供.颈动脉支架治疗前后VE-ASL结果有明显差异.结论 在颈内动脉狭窄、闭塞的患者,VE-ASL可以无创地显示侧支循环的存在、来源及远端功能,可用于评价颈动脉支架植入后的治疗效果. Objective To evaluate collateral flows using vessel encoded arterial spin labeling (VE-ASL) perfusion imaging. Methods VE-ASL was achieved to assess the presence and function of collateral flow on patients with internal carotid artery (ICA) stenosis. The presence of the anterior and posterior collateral flow was demonstrated by flow patterns of the A1 segment and posterior communicating artery (PCoA). Distal function of collateral flow of stenotic hemisphere was categorized as adequate ( cerebral blood flow ≥10 ml · min-1·100 g-1 ) or deficient (cerebral blood flow < 10 ml · min-1· 100 g-1 ). The results were compared with magnetic resonance angiography (MRA) and intraarterial digital subtraction angiography (DSA) in crosstable by using Kappa values. The VE-ASL before and after ICA stent therapy were compared. Results The Kappa values of the flow patterns of AI segment and PCoA between VE-ASL and MRA were 0. 746 and 0. 700. The Kappa value of the function of collaterals using VE-ASL and DSA was 914. VE-ASL showed collateral flow via leptomeningeal anastomoses. VE-ASL changed significantly after ICA steat therapy. Conclusion VE-ASL reveals the presence and distal function of collateral flow, which helps to evaluate the efficacy of ICA steat therapy.
语种: 中文
原文出处: 查看原文
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内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/42859
Appears in Collections:北京大学第一临床医学院_医学影像科_期刊论文

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作者单位: 1.北京大学第一医院医学影像科,100034
2.北京大学前沿交叉学科研究院功能成像研究中心
3.北京大学第一医院神经外科
4.Center for Functional Magnetic Resonance Imaging and Departments of Radiology and Psychiatry,University of California,San Diego,La Jolla,California,United state8
5.北京大学第一医院神经内科
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