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学科主题: 临床医学
题名:
2型糖尿病患者颈动脉内中膜厚度与动脉僵硬度随访观察
其他题名: Analyses of carotid intima-media thickness and quantitative arterial stiffness in type 2 diabetes mellitus patients with follow-ups
作者: 陈路增1; 王彬1; 张惠1; 杨建梅1
关键词: 超声检查 ; 糖尿病,2型 ; 僵硬度 ; 内中膜厚度 ; Ultrasonography ; Diabetes mellitus,type 2 ; Stiffness ; Intima-media thickness
刊名: 中华医学杂志
发表日期: 2013
DOI: 10.3760/cma.j.issn.0376-2491.2013.12.012
卷: 93, 期:12, 页:927-929
收录类别: 中国科技核心期刊 ; 中文核心期刊 ; CSCD
文章类型: Journal Article
摘要: 目的 探讨2型糖尿病患者颈动脉僵硬度变化规律及其与内中膜厚度(IMT)的关系.方法 2009年5月7至30日,北京大学第一医院内分泌科共72例2型糖尿病患者纳入研究,所有患者行颈动脉超声检查,应用射频信号血管内中膜分析技术(QIMT)软件描记颈动脉IMT,动脉僵硬度测量技术(QAS)软件测量颈动脉顺应性系数(CC)、僵硬度系数(α)、血管直径归一化硬度系数(β)、脉搏波传播速度(PWV)等参数.患者控制血糖、血脂、血压水平达到正常标准.于2011年2月再次行超声检查,测量以上参数.对以上数据进行分析.结果 与2009年超声检查比较,2011年超声检查双侧颈动脉CC明显升高(左侧0.9±0.4比1.1±0.4,P=0.016;右侧1.1±0.5比1.2±0.5,P=0.012).双侧颈动脉IMT有升高趋势,α、β、PWV有降低趋势,但差异无统计学意义.同一时间点分析糖尿病患者颈动脉IMT与动脉僵硬度参数无相关性.结论 控制血糖、血脂、血压能降低2型糖尿病患者颈动脉僵硬度.2型糖尿病患者颈动脉IMT与动脉僵硬度参数没有相关性. Objective To explore the change pattern of carotid stiffness and its relationship between intima-media thickness (IMT) in type 2 diabetes mellitus (T2DM).Methods Quantitative intima-media thickness (QIMT) and quantitative arterial stiffness (QAS) were performed on bilateral carotids of 72 T2DM patients in May 2009 and February 2011 separately.IMT,compliance coefficent (CC),α,β and pulse wave velocity (PWV) were measured.Their relationship was analyzed.Results Comparing with ultrasound result in 2009,CC of bilateral carotids increased (left 0.9 ± 0.4 vs 1.1 ± 0.4,p =0.016 ; right 1.1 ± 0.5 vs 1.2±0.5,P =0.012).IMT increased while α,β and PWV decreased (P >0.05) in 2011.No correlation existed between carotid IMT and QAS parameters.Conclusion The glycemic,lipid and blood pressure controls decrease the carotid stiffness of patients with T2DM.Carotid IMT and stiffness
语种: 中文
原文出处: 查看原文
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内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/43500
Appears in Collections:北京大学第一临床医学院_超声诊断中心_期刊论文

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作者单位: 1.100034,北京大学第一医院超声中心
2.100034,北京大学第一医院内分泌科

Recommended Citation:
陈路增,王彬,张惠,等. 2型糖尿病患者颈动脉内中膜厚度与动脉僵硬度随访观察[J]. 中华医学杂志,2013,93(12):927-929.
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