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学科主题: 临床检验诊断学
题名:
SARS病房工作的医护人员血清中特异抗体测定分析
其他题名: Investigation on serum specific anti-SARS coronavirus IgM and IgG antibodies in physicians and nurses working in SARS wards
作者: 冯珍如1; 徐国宾1; 刘平1; 王广发1; 王贵强1; 徐小元1
关键词: 严重急性呼吸综合症 ; ELISA ; ⅡFA ; 抗体 ; SARS ; enzyme linked immunosorbent assay ; indirect immunofluorescence assay ; antibody
刊名: 中国现代医学杂志
发表日期: 2004
DOI: 10.3969/j.issn.1005-8982.2004.12.004
卷: 14, 期:12, 页:12-15
收录类别: 中国科技核心期刊 ; 中文核心期刊 ; CSCD
文章类型: Journal Article
摘要: 目的检测密切接触SARS患者的医护人员血清中SARS病毒IgM及IgG抗体的水平,对SARS病毒有无隐性感染作初步调查.方法分别用酶联免疫吸附法(Enzyme linked immunosorbent assay,ELISA)和间接免疫荧光法(Indirect immunofluorescence assay,ⅡFA)检测200例正常人,200例在SARS病房工作1个月的医护人员血清中SARS病毒IgM及IgG抗体的水平.结果正常人及医护人员血清中未检测到SARS病毒IgM及IgG抗体.结论不同于普通的流行性传染性疾病,SARS病毒可能不具有隐性感染性. Objectives: To detect serum specific anti-SARS coronavirus IgM and IgG antibodies in physicians and nurses working in SARS wards, and investigate the status of subclinical infection of SARS coronavirus. Methods: Serum anti-SARS coronavirus antibodies (IgM and IgG) were measured by enzyme linked immunosorbent assay and indirect immunofluorescence assay in 200 normal subjects, 200 physicians and nurses working in SARS wards for one month. Results: Serum anti-SARS comavirus antibodies (IgM and IgG) were not found in normal subjects and the close contacts. Conclusions: Unlike most of the epidemic infectious diseases, subclinical infection may not occur in SARS coronavirus infection.
语种: 中文
原文出处: 查看原文
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内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/43562
Appears in Collections:北京大学第一临床医学院_检验科_期刊论文

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作者单位: 1.北京大学第一医院,检验科,北京,100034
2.北京大学第一医院,呼吸科,北京,100034
3.北京大学第一医院,感染疾病科,北京,100034

Recommended Citation:
冯珍如,徐国宾,刘平,等. SARS病房工作的医护人员血清中特异抗体测定分析[J]. 中国现代医学杂志,2004,14(12):12-15.
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