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学科主题: 药剂学
题名:
万古霉素在儿科患者中的临床用药调查
其他题名: Clinical investigation of vancomycin used in pediatric patients
作者: 盛晓燕1; 杨玉洁1; 陈超阳1; 闫立国1; 周颖1; 崔一民1
关键词: 万古霉素 ; 儿科患者 ; 合理用药 ; 肺部感染 ; vancomycin ; pediatric patients ; drug rational use ; pulmo-nary infection
刊名: 中国临床药理学杂志
发表日期: 2014
DOI: 10.13699/j.cnki.1001-6821.2014.09.020
期: 9, 页:816-818
收录类别: 中国科技核心期刊 ; 中文核心期刊 ; CSCD
文章类型: Journal Article
摘要: 目的:评价万古霉素在儿科患者中的使用情况及特点,促进临床合理用药。方法通过回顾性分析静脉用万古霉素的住院患儿,提取患儿的病原学检查、疾病情况、药物治疗监测情况、用药时间、疗效等数据进行统计分析。结果2013年,94例次患儿病例中,经验治疗比例为65.96%;有效率为78.72%;用药原因中肺部感染所占比例最高34.86%;微生物及药敏送检率为96.81%,阳性结果中葡萄球菌占20.81%(36/173);治疗药物监测比例为17.02%。结论临床用万古霉素以经验用药为多,使用基本合理,但用药及监测细节上仍存在一些问题。 Objective To investigate the use of vancomycin in pediatric patients and promote the rational use of vancomycin.Methods By retrospective analysis, data were extracted from medical records of 94 pediatric patients in terms of etiology check , diseases , therapeutic drug monitoring ( TDM ) , medication duration , therapeutic efficacy , etc.Results The treatment of vancomycin in 65.96%was based on experi-ence and the effective rate is 78.72%.The biggest reason to use vanco-mycin is pulmonary infection 34.86%.96.81% of the patients comple-ted etiology check and drug sensitive test , and staphylococcal infection accounts for 20.81%( 36/173 ) of the positive results.17.02% of the patients completed therapeutic drug monitoring.Conclusion The treat-ment of vancomycin is mainly based on experience.Most of the usage is rational , but some details in the usage and TDM should be paid attention.
语种: 中文
原文出处: 查看原文
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内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/43885
Appears in Collections:北京大学第一临床医学院_药剂科_期刊论文

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作者单位: 1.北京大学 第一医院 药剂科,北京,100034
2.中国药科大学 药学院 临床药学系,南京,211198

Recommended Citation:
盛晓燕,杨玉洁,陈超阳,等. 万古霉素在儿科患者中的临床用药调查[J]. 中国临床药理学杂志,2014(9):816-818.
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