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学科主题: 药理学
题名:
2012年中国男性尿路感染细菌分布及耐药状况
其他题名: Antimicrobial susceptibility pattern and epidemiology of male urinary tract infections in China, 2012
作者: 阮亘杰1; 郑波1; 刘玉村1
关键词: 尿路感染 ; 男性 ; 细菌耐药 ; 抗菌药物 ; urinary tract infection ; male ; drug resistance
刊名: 中国临床药理学杂志
发表日期: 2015
DOI: 10.13699/j.cnki.1001-6821.2015.11.026
期: 11, 页:1007-1013,1021
收录类别: 中国科技核心期刊 ; 中文核心期刊 ; CSCD
文章类型: Journal Article
摘要: 目的:总结我国2012年男性尿标本来源细菌分布及耐药状况。方法常规方法培养分离男性尿标本中的细菌,采用纸片法、微量稀释法或E-test法测定细菌药物的敏感性。结果2012年从557家三级医院和232家二级医院的男性尿标本中分离出61295株细菌,排在前4位的分别是大肠埃希菌(20357株,33.2%)、粪肠球菌(5280株,8.6%)、肺炎克雷伯杆菌(5249株,8.6%)和屎肠球菌(4516株,7.4%)。其中,三级医院排名前4位的分别是大肠埃希菌、粪肠球菌、肺炎克雷伯菌和屎肠球菌,二级医院前4位的是大肠埃希菌、铜绿假单胞菌、肺炎克雷伯菌和粪肠球菌。大肠埃希菌、肺炎克雷伯菌和阴沟肠杆菌对头孢噻肟的耐药率均超过70%,对左氧氟沙星的耐药率分别为63.8%,40.9%和35.7%。屎肠球菌对万古霉素和替考拉宁的耐药率为4.2%和4.0%,粪肠球菌对万古霉素和替考拉宁的耐药率为1.1%和2.8%。结论男性尿路感染主要致病菌仍以大肠埃希菌为主,二、三级医院间从菌种分布和耐药状况上有一定差异。 Objective To investigate the bacterial distribution and resistance to antibiotic of male urinary tract infections in China,2012.Methods The urine specimens from the tertiary hospitals and the second class hospitals were routinely isolated and identified.Disc diffusion test, MIC test and E -test were used to detect the antimicrobial sensitivity.Results All the clinical stains isolated from 557 tertiary hospitals and 232 second class hospitals.A total of 61293 pathogenic strains were co-llected from male urine specimen, which included E.coli 20357strains ( 33.2%) , E.faecalis 5280 strains ( 8.6%) , K.pneumonia 5249 strains (8.6%) and E.faecium 4516 strains (7.4%).In tertiary hos-pital, The top four bacteria were E.coli, E.faecalis.K.pneumonia and E.faecium, and in second class hospitals were E.coli, P.aeruginosa, K.pneumonia and E.faecalis.The resistant rate of E.coli, K.pneumo-nia and E.cloaecae strains to cefotaxime were above 70%.The resistant rate to levofloxacin were 63.8%, 40.9%and 35.7%, respectively.The 4.2%and 4.0%of E.faecium isolates were resistant to vancomycin and teicoplanin, respectively.The 1.1% and 2.8% of E.faecalis isolates were resistant to vancomyicin and teicoplanin, respectively.Conclusion E.coli were predominant organism in male urinary tract infections in China.There were some difference in bacterial distribution and resistance between the tertiary hospitals and second class hospitals.
语种: 中文
原文出处: 查看原文
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内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/44498
Appears in Collections:北京大学第一临床医学院_临床药理研究所_期刊论文

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作者单位: 1.北京大学第一医院,临床药理研究所,北京 100034
2.北京大学第一医院普通外科,北京,100034

Recommended Citation:
阮亘杰,郑波,刘玉村. 2012年中国男性尿路感染细菌分布及耐药状况[J]. 中国临床药理学杂志,2015(11):1007-1013,1021.
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