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学科主题: 泌尿外科学
题名:
Partin tables对国人前列腺癌的预测价值
其他题名: Predictive accuracy of different Partin tables in Chinese prostate cancer patients
作者: 蔡林; 周利群; 何志嵩; 李宁忱; 宋毅
关键词: 前列腺肿瘤 ; Partintables ; 预测 ; 病理 ; Prostatic neoplasm ; Partin tables ; Prediction ; Pathology
刊名: 中华泌尿外科杂志
发表日期: 2009
DOI: 10.3760/cma.j.issn.1000-6702.2009.03.018
卷: 30, 期:3, 页:202-206
收录类别: 中国科技核心期刊 ; 中文核心期刊 ; CSCD
文章类型: Journal Article
摘要: 目的 验证基于美国人群样本资料的Partin tables(1997)、Partin tables for the new millennium(2001)及Partin tables update(2007)在预测国人前列腺癌术后病理特征的准确性.方法 1997年1月至2007年6月,连续109例临床局限件前列腺癌患者接受耻骨后前列腺癌根治术或腹腔镜下前列腺癌根治术,术后病理报告包括是否为器官局限性癌及有无包膜侵犯、精囊侵犯或淋巴结转移,并符合Partin tables的纳入标准.根据临床分期、穿刺活检Gleason评分、术前血清PSA,应用上述3个Partin tables预测上述病理特征.采用受试者工作特征曲线(ROC)分析方法分别检验3个Partin tables预测术后病理特征的准确性.ROC曲线下面积>0.7时判断相应病理特征的预测准确性具有理想的临床使用价值.结果 109例中器官局限性癌、包膜侵犯及精囊侵犯的发生率分别为70%(76/109)、17%(19/109)及13%(14/109),无淋巴结转移者.Partin tables 1 997预测器官局限、包膜侵犯及精囊侵犯的ROC曲线下面积分别为0.727、0.654及0.811,Partin tables 2001预测的ROC曲线下面积分别为0.693、0.633及0.835.Partin tables 2007预测的ROC曲线下面积分别为0.669、0.611及0.778.结论 3个Partin tables对国人前列腺癌术后精囊侵犯的预测均较准确,但对包膜侵犯的预测准确性均较低,仅Partin tables 1997对器官局限性癌的预测较准确. Objective To validate the Partin table 1997,2001 and 2007 for their accuracy in predicting pathologic stage in Chinese prostate cancer patients.Methods From January 1997 to June 2007,109 consecutive patients with clinically localized prostate carcinoma underwent open retropubic or laparoscopic radical prostatectomies and met all inclusion criteria well enrolled.Receiver operating characteristic(ROC)analysis was performed tO test the predictive accuracy of organ confined disease (0CD),extraprostatic extension(EPE),seminal vesicle involvement(SVI)and lymph node involvement(LNI). Results OCD,EPE,SVl and LNl were noted in 70%,17%,13%and 0%of cases respectively.The area under curve(AUC)of ROC for Partin table 1997 was 0.727,0.654 and 0.811for 0CD.EPE and SVl respectively,and was 0.693,0.633 and 0.835 for Partin table 2001 and 0.669.0.611 and 0.778 for Partin table 2007.Conclusions Partin tables 1997,2001 and 2007 are able to accurately predict the pathologic feature of seminal vesicle involvement.However,only Partin table 1997 can more accurately predict organ confined disease in this external validation for Chinese patients.
语种: 中文
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内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/44999
Appears in Collections:北京大学第一临床医学院_泌尿外科_期刊论文

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作者单位: 北京大学第一医院泌尿外科北京大学泌尿外科研究所,100034

Recommended Citation:
蔡林,周利群,何志嵩,等. Partin tables对国人前列腺癌的预测价值[J]. 中华泌尿外科杂志,2009,30(3):202-206.
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