In the practice of medical and nosocomial infection management, the need for nosocomial infection control standards is increasing day by day. 38 nosocomial infection control standards have been approved and initiated and 8 released since the establishment of the Professional Committee of Nosocomial Infection Control Standards under the Ministry of Health in 2006 till now. At the present stage, the formulation, publicity, and implementation of nosocomial infection control standards of China are in accordance with the Management Measures for Health Standards, and standards having been released play a promoting role in nosocomial infection management. However, in terms of the formulation and implementation of nosocomial infection control standards, there are still problems such as inadequate evidence of evidence-based medicine, ambiguous standard category, poor planning for standard approval and initiation, and weak implementation strength needing to be enhanced. As a result, it is an urgent need to set up a framework system for nosocomial infection control standards in China in order to institutionally and legally guarantee the implementation of such standards.