北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 北京大学第一临床医学院  > 期刊论文
学科主题: 临床医学
题名:
多重耐药菌感染干预效果多中心研究
其他题名: Multicenter study on effectiveness of intervention in multidrug-resistant organism infection
作者: 贾会学1; 胡必杰1; 吴安华1; 徐英春1; 张秀月1; 侯铁英1; 宗志勇1; 李卫光1; 杨怀1; 杨芸1; 刘运喜1; 建国1; 陆群1; 李六亿1
关键词: 多重耐药菌 ; MDRO ; 医院感染 ; 干预 ; 效果 ; 多中心研究 ; multidrug-resistant organism ; healthcare-associated infection ; hospital-onset infection ; intervention ; effectiveness ; multicenter study
刊名: 中国感染控制杂志
发表日期: 2015
DOI: 10.3969/j.issn.1671-9638.2015.08.005
期: 8, 页:524-529
收录类别: 中国科技核心期刊
文章类型: Journal Article
摘要: 目的:了解采取干预措施对降低多重耐药菌(MDRO)感染的效果。方法2013年10月—2014年9月对我国12个省市46所医院进行调查,其中2013年10月—2014年3月为基线调查阶段(干预前),该阶段未采取任何干预措施;2014年4—9月为实施干预措施阶段(干预后),比较干预前后 MDRO 感染情况及防控措施依从性。结果共监测34081例病例,住院总日数为302818 d,MDRO 医院发病的感染(HOI)1122例次,HOI 例次发病率为3.71‰。各种 MDRO 以 CRAB HOI 例次日发病率(2.47‰)最高,各重症监护病房(ICU)以外科 ICU HOI 例次日发病率(5.55‰)最高。总体 MDRO HOI 例次日发病率由干预前的3.96‰,降至干预后的3.53‰,差异有统计学意义(P =0.03);干预后呼吸 ICU 和急诊 ICU HOI 例次日发病率均低于干预前(均 P <0.05)。干预后各项防控措施:实施隔离、同种病原体隔离、悬挂隔离标识、手卫生、戴手套、物品专用依从率,以及医生、护士、保洁员知晓率均明显提高,差异均有统计学意义(均 P <0.05)。结论通过采取 MDRO 防控措施及对其依从性进行监测,可有效提升各措施的依从性,降低 MDRO HOI 发病率。 Objective To evaluate the effectiveness of intervention measures in reducing infection caused by multidrug-resistant organisms (MDROs).Methods From October 2013 to September 2014,a survey was conducted among 46 hospi-tals of 12 provinces and cities in China,from October 2013 to March 2014 was baseline investigation stage(before interven-tion),from April 2014 to September 2014 was intervention stage(after intervention),the occurrence of MDRO infection and compliance to prevention and control measures before and after intervention were compared.Results A total of 34 081 cases were monitored,the overall patient-days were 302 818 d,there were 1 122 episodes of hospital-onset infection (HOI),HOI case rate was 3.71‰ .Of various MDROs,infection case rate caused by carbapenem-resistant Acinetobacter baumannii per 1 000 patient-days was highest (2.47‰);Of different intensive care units(ICUs),incidence of HOI per 1 000 patient-days was highest in surgical ICUs (5.55‰).The overall MDRO HOI case rate decreased from 3.96/1 000 patient-days before intervention to 3.53 / 1 000 patient-days after intervention,the difference was significant (P =0.03). HOI case rate per 1 000 patient-days in respiratory and emergency ICUs decreased significantly after intervention(both P <0.05 ).The compliance to prevention and control measures (isolation,hanging isolation signs,hand hygiene,wearing gloves,item exclusive use),as well as doctors,nurses,and cleaning staff awareness enhanced significantly after interven-tion (all P <0.05).Conclusion By carrying out prevention and control measures on MDROs and monitoring the compliance to various measures,compliance to various measures can be improved,and MDRO HOI can decrease effectively.
语种: 中文
原文出处: 查看原文
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/48118
Appears in Collections:北京大学第一临床医学院_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: 1.北京大学第一医院,北京,100034
2.复旦大学附属中山医院,上海,200032
3.中南大学湘雅医院,湖南 长沙,410008
4.北京协和医 院,北京,100032
5.中国医科大学附属盛京医 院,辽宁沈阳,110004
6.广东省人民医 院,广东广州,510008
7.四川大学华西医院,四川 成都,610041
8.山东省立医院,山东 济南,250021
9.贵州省人民医院,贵州 贵阳,550002
10.山西医学科学院山西大医院,山西 太原,030001
11.解放军总医院,北京,100853
12.郑州大学第一附属医院,河南 郑州,450052
13.浙江大学医学院附属第二医院,浙江 杭州,310009

Recommended Citation:
贾会学,胡必杰,吴安华,等. 多重耐药菌感染干预效果多中心研究[J]. 中国感染控制杂志,2015(8):524-529.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[贾会学]'s Articles
[胡必杰]'s Articles
[吴安华]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[贾会学]‘s Articles
[胡必杰]‘s Articles
[吴安华]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace