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学科主题: 临床医学
题名:
新生儿重症监护病房医院感染流行病学多中心研究
其他题名: Multicenter study on epidemiology of healthcare-associated infection in neonatal intensive care units
作者: 贾会学1; 殷环1; 吴安华1; 胡必杰1; 张秀月1; 侯铁英1; 宗志勇1; 李卫光1; 杨怀1; 杨芸1; 刘运喜1; 文建国1; 陆群1; 李六亿1
关键词: 新生儿监护病房 ; NICU ; 医院感染 ; 例次感染率 ; 日感染率 ; 流行病学 ; 多中心研究 ; neonatal intensive care unit ; healthcare-associated infection ; infection case rate ; infection rate per 1 000 patient-days ; epidemiology ; multicenter study
刊名: 中国感染控制杂志
发表日期: 2015
DOI: 10.3969/j.issn.1671-9638.2015.10.001
期: 10, 页:649-653
收录类别: 中国科技核心期刊
文章类型: Journal Article
摘要: 目的:了解我国三级甲等综合医院新生儿监护病房(NICU)医院感染的流行特点,为预防和控制新生儿医院感染提供科学依据。方法以多中心研究的方式,选取全国9省17所医院,按照统一的诊断标准和方法对2013年10月—2014年9月 NICU 住院新生儿的医院感染情况进行前瞻性监测。结果共监测12998例 NICU住院新生儿,发生436例次医院感染,例次发病率为3.35%,住院总日数为126125 d,日发病率为3.46‰。新生儿医院感染例次发病率随新生儿出生体重的增加而下降(χ2=291.55,P <0.001)。不同规模 NICU 新生儿医院感染发病率比较,差异有统计学意义(χ2=49.77,P <0.001),床位数>30张的 NICU 新生儿医院感染例次发病率和日发病率最高;NICU 新生儿医院感染例次发病率以西南地区(10.36%)最高,日发病率以华南地区(10.52‰)最高。感染部位以下呼吸道和血液为主;感染病原体以肺炎克雷伯菌、大肠埃希菌、鲍曼不动杆菌为主。结论我国NICU 不同出生体重组、不同规模、不同地区的新生儿医院感染发病率不同,应继续加强监测,根据感染特点指导各项防控措施的落实。 Objective To investigate the epidemiological characteristics of healthcare-associated infection (HAI)in neo-natal intensive care units(NICUs)of tertiary first-class hospitals in China,and provide scientific evidence for the prevention and control of neonatal HAI.Methods 17 hospitals in 9 provinces were selected for multicenter study,HAI occurred in neonates at NICUs from October 2013 to September 2014 were surveyed prospectively according to the uniform diagnostic criteria and methods.Results A total of 12 998 neonates were monitored,436 (3.35%)HAI cases occurred,the total patient-days were 126 125 days,incidence of infection was 3.46/1 000 patient-days.HAI cases rate decreased with the in-crease of birth weight (χ2 =291.55,P <0.001).The difference of HAI rate in neonates at different sizes of ICUs were significantly different(χ2 =49.77,P <0.001),infection case rate and infection incidence per 1 000 patient-days were both highest in NICUs with >30 beds;HAI case rate was highest in southwest region(10.36%),infection rate per 1 000 pa-tient-days was the highest in southern China(10.52‰).Lower respiratory tract and bloodstream were the main infection sites;the major pathogens for infection were Klebsiella pneumoniae ,Escherichia coli ,and Acinetobacter baumannii . Conclusion The incidences of HAI in NICUs are different among neonates of different birth weight,at different sizes of ICUs,and at ICUs of different regions,surveillance should be strengthened,prevention and control measures should imple-mented according to infection characteristics.
语种: 中文
原文出处: 查看原文
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内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/48122
Appears in Collections:北京大学第一临床医学院_期刊论文

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作者单位: 1.北京大学第一医院,北京,100034
2.中南大学湘雅医院,湖南 长沙,410008
3.复旦大学附属中山医院,上海,200032
4.中国医科大学附属盛京医院,辽宁 沈阳,110004
5.广东省人民医院,广东 广州,510008
6.四川大学华西医院,四川成都,610041
7.山东省立医院,山东 济南,250021
8.贵州省人民医院,贵州 贵阳,550002
9.山西医学科学院山西大医院,山西 太原,030001
10.10 解放军总医院,北京,100853
11.11 郑州大学第一附属医院,河南 郑州,450052
12.12 浙江大学医学院附属第二医院,浙江 杭州,310009

Recommended Citation:
贾会学,殷环,吴安华,等. 新生儿重症监护病房医院感染流行病学多中心研究[J]. 中国感染控制杂志,2015(10):649-653.
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