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学科主题: 临床医学
题名:
Selective resection of dorsal nerves of penis for premature ejaculation
作者: Zhang, G. -X.; Yu, L. -P.; Bai, W. -J.; Wang, X. -F.
关键词: circumcision ; intravaginal ejaculation latency time ; premature ejaculation ; selective resection of the dorsal nerve
刊名: INTERNATIONAL JOURNAL OF ANDROLOGY
发表日期: 2012-12-01
DOI: 10.1111/j.1365-2605.2012.01296.x
卷: 35, 期:6, 页:873-879
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Andrology
研究领域[WOS]: Endocrinology & Metabolism
关键词[WOS]: MALE SEXUAL FUNCTION ; CIRCUMCISION ; INVENTORY ; EFFICACY ; MEN
英文摘要:

Premature ejaculation (PE) is one of the most prevalent male sexual dysfunctions. Selective resection of the dorsal nerve (SRDN) of penis has recently been used for the treatment of PE and has shown some efficacy. To further clarify the efficacy and safety of SRDN on PE, we performed a preliminary, randomized, placebo-controlled clinical observational study. Persons with the complaints of rapid ejaculation, asking for circumcision because of redundant foreskin, intravaginal ejaculation latency time (IELT) within 2 min, not responding to antidepressant medication or disliking oral medication were randomly enrolled in two groups. From April 2007 to August 2010, a total of 101 eligible persons were enrolled, 40 of them received SRDN which dorsal nerves of the penis were selectively resected, and those (n = 61) enrolled in the control group were circumcised only. IELT and the Brief Male Sexual Function Inventory (BMSFI) questionnaire were implemented pre- and post-operatively for the evaluation of the effect and safety of the surgery. There are no statistically significant differences in the baseline data including mean ages, mean IELTs, perceived control abilities and the BMSFI mean scores between the two groups. With regard to the post-operative data of the surgery, both IELTs and perceived control abilities were significantly increased after SRDN (1.1 +/- 0.9 min vs. 3.8 +/- 3.1 min for pre- and post-operative IELT, respectively, p < 0.01),whereas the post-operative results were not significantly improved for the control group (1.2 +/- 0.7 min vs. 1.5 +/- 1.1 min, p > 0.05). Also, there were no statistically significant differences both in BMSFI composite and subscale scores between the two groups after surgery. Hence, we conclude that SRDN is effective in delaying ejaculation and improving ejaculatory control, whereas erectile function is not affected. The results imply that SRDN may be an alternative method for the treatment of PE for some patients.

语种: 英语
WOS记录号: WOS:000311435200013
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/49945
Appears in Collections:北京大学第二临床医学院_泌尿外科_期刊论文

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作者单位: Peking Univ, Peoples Hosp, Dept Urol, Beijing 100871, Peoples R China

Recommended Citation:
Zhang, G. -X.,Yu, L. -P.,Bai, W. -J.,et al. Selective resection of dorsal nerves of penis for premature ejaculation[J]. INTERNATIONAL JOURNAL OF ANDROLOGY,2012,35(6):873-879.
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