IR@PKUHSC  > 北京大学第二临床医学院
学科主题临床医学
Histological Analysis of Single Peripheral Nerve Fiber in Acute Nerve Elongation Process
Wang, Weibin; Zhang, Peixun; Yan, Jiazhi; Han, Na; Kou, Yuhui; Zhang, Hongbo; Jiang, Baoguo
关键词Peripheral Nerve Histology Nerve Fibers Nerve Elongation
刊名ARTIFICIAL CELLS BLOOD SUBSTITUTES AND BIOTECHNOLOGY
2010
DOI10.3109/10731191003670558
38期:4页:165-168
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Biotechnology & Applied Microbiology ; Engineering, Biomedical ; Materials Science, Biomaterials
资助者Chinese National Natural Science Fund for Outstanding Youth ; Chinese 973 Project Planning ; Chinese National Natural Science Youth Fund ; Beijing City Science &amp ; Technology New Star Classification ; Chinese Ministry of Education for Doctor Position New Teacher ; Chinese National Natural Science Fund for Outstanding Youth ; Chinese 973 Project Planning ; Chinese National Natural Science Youth Fund ; Beijing City Science &amp ; Technology New Star Classification ; Chinese Ministry of Education for Doctor Position New Teacher
研究领域[WOS]Biotechnology & Applied Microbiology ; Engineering ; Materials Science
关键词[WOS]SCIATIC-NERVE ; INJURY ; MORPHOLOGY ; RATS
英文摘要

To observe the histological alterations of single nerve fiber structures after nerve elongation by employing a rabbit peroneal nerve stretching model. 14 rabbits weighing mean 3. 0 kg (2.02-3.31kg.) were used in the experiment. Two rabbits were used as control when only a sham operation was done (group one, 0% stretch). Acute stretching of the peroneal nerves to elongate them by 10% was done in 6 rabbits (group two, 10% elongation) and by 20% (group three, 20% elongation) in another 6 rabbits. All animals were evaluated by tissue staining technology in a teased-fiber study. The internodal lengths were measured, and nodes of Ranvier and Schmidt-Lanterman notch were observed. The nerve fiber length was increased after stretching. The mean internodal length was 1208.31 mu m in group one, 1347.26 mu m in group two, and 1411.35 mu m in group three. Compared with the control group, mean internodal length was elongated by 11.50% in group two and 16.80% in group three. The difference was statistically significant. The node of Ranvier and Schmidt-Lanterman notch was wider in both group two and group three. Rupture of nerve fiber at the node of Ranvier was observed in group three. The peroneal nerve in rabbits can adapt to mild stretching by internodal length elongation. Elongation by 20% will cause structural rupture and therefore is the limit for nerve elongation.

语种英语
所属项目编号30625036 ; 2005CB522604 ; 30801169 ; A-2008-10 ; 20070001780
资助者Chinese National Natural Science Fund for Outstanding Youth ; Chinese 973 Project Planning ; Chinese National Natural Science Youth Fund ; Beijing City Science &amp ; Technology New Star Classification ; Chinese Ministry of Education for Doctor Position New Teacher ; Chinese National Natural Science Fund for Outstanding Youth ; Chinese 973 Project Planning ; Chinese National Natural Science Youth Fund ; Beijing City Science &amp ; Technology New Star Classification ; Chinese Ministry of Education for Doctor Position New Teacher
WOS记录号WOS:000281151900001
Citation statistics
Cited Times:1[WOS]   [WOS Record]     [Related Records in WOS]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/49964
Collection北京大学第二临床医学院
作者单位Peking Univ, Peoples Hosp, Dept Trauma Orthopead, Beijing 100044, Peoples R China
Recommended Citation
GB/T 7714
Wang, Weibin,Zhang, Peixun,Yan, Jiazhi,et al. Histological Analysis of Single Peripheral Nerve Fiber in Acute Nerve Elongation Process[J]. ARTIFICIAL CELLS BLOOD SUBSTITUTES AND BIOTECHNOLOGY,2010,38(4):165-168.
APA Wang, Weibin.,Zhang, Peixun.,Yan, Jiazhi.,Han, Na.,Kou, Yuhui.,...&Jiang, Baoguo.(2010).Histological Analysis of Single Peripheral Nerve Fiber in Acute Nerve Elongation Process.ARTIFICIAL CELLS BLOOD SUBSTITUTES AND BIOTECHNOLOGY,38(4),165-168.
MLA Wang, Weibin,et al."Histological Analysis of Single Peripheral Nerve Fiber in Acute Nerve Elongation Process".ARTIFICIAL CELLS BLOOD SUBSTITUTES AND BIOTECHNOLOGY 38.4(2010):165-168.
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