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学科主题: 临床医学
题名:
Basaloid squamous cell carcinoma of the maxillary gingiva: A case report and review of the literature
作者: Xie, Shule1; Bredell, Marius2; Yang, Hongyu1; Shen, Shiyue1; Yang, Huijun1
关键词: basaloid squamous cell carcinoma ; gingival carcinoma ; squamous cell carcinoma ; immunohistochemistry
刊名: ONCOLOGY LETTERS
发表日期: 2014-09-01
DOI: 10.3892/ol.2014.2318
卷: 8, 期:3, 页:1287-1290
收录类别: SCI
文章类型: Review
WOS标题词: Science & Technology
类目[WOS]: Oncology
研究领域[WOS]: Oncology
关键词[WOS]: ORAL-MUCOSA ; HEAD ; NECK ; PROGNOSIS
英文摘要:

Basaloid squamous cell carcinoma (BSCC) is a rare, but distinct histologic variant of squamous cell carcinoma in the head and neck region. It is considered to have a poor prognosis due to its aggressive behavior and tendency to metastasize. The usual sites of BSCC are the floor of the mouth, hypopharynx and base of the tongue, and according to the English-language literature its presentation in the gingiva is somewhat uncommon. In the current report, the unusual case of a 40-year-old male is presented; the patient exhibited a painless irregular mass in the maxillary gingiva, which infiltrated the maxillary sinus, as observed by computed tomography. Hematoxylin and eosin-stained sections revealed a diagnosis of BSCC with typical central necrosis in the cancer nests, which contained basaloid and squamous cells. Immunohistochemistry revealed that p63 was weakly positive, high molecular weight cytokeratin (CK) was focally positive, and S-100, CK7, CK14 and vimentin were negative. It must be noted that histopathology results may be incorrectly interpreted as adenoid cystic carcinoma, undifferentiated carcinoma and basal cell adenocarcinoma.

语种: 英语
所属项目编号: S2012010010382 ; JCY20130402114702120
项目资助者: Department of Cranio-Maxillofacial and Oral Surgery, University Hospital Zurich (Zurich, Switzerland) ; Guangdong Province Nature Science Foundation ; Shenzhen Science and Research Innovation Foundation
WOS记录号: WOS:000340854600068
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/50008
Appears in Collections:北京大学深圳医院_期刊论文

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作者单位: 1.Peking Univ, Shenzhen Hosp, Dept Oral & Maxillofacial Surg, Shenzhen 518001, Guangdong, Peoples R China
2.Univ Zurich Hosp, Dept Craniomaxillofacial & Oral Surg, CH-8091 Zurich, Switzerland

Recommended Citation:
Xie, Shule,Bredell, Marius,Yang, Hongyu,et al. Basaloid squamous cell carcinoma of the maxillary gingiva: A case report and review of the literature[J]. ONCOLOGY LETTERS,2014,8(3):1287-1290.
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