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学科主题临床医学
Association Between Passive and Active Smoking and Incident Type 2 Diabetes in Women
Curhan, Gary C.1,2,3; Zhang, Luxia1,2,3,4; Hu, Frank B.1,2,5,6; Rimm, Eric B.1,2,5,6; Forman, John P.1,2,3
刊名DIABETES CARE
2011-04-01
DOI10.2337/dc10-2087
34期:4页:892-897
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Endocrinology & Metabolism
研究领域[WOS]Endocrinology & Metabolism
关键词[WOS]ENVIRONMENTAL TOBACCO-SMOKE ; CIGARETTE-SMOKING ; PROSPECTIVE COHORT ; RISK ; EXPOSURE ; POPULATION ; HEALTH ; MEN ; MELLITUS ; DISEASES
英文摘要

OBJECTIVE-Accumulating evidence has identified a positive association between active smoking and the risk of diabetes, but previous studies had limited information on passive smoking or changes in smoking behaviors over time. This analysis examined the association between exposure to passive smoke, active smoking, and the risk of incident type 2 diabetes among women.

RESEARCH DESIGN AND METHODS-This is a prospective cohort study of 100,526 women in the Nurses′ Health Study who did not have prevalent diabetes in 1982, with follow-up for diabetes for 24 years.

RESULTS-We identified 5,392 incident cases of type 2 diabetes during 24 years of follow-up. Compared with nonsmokers with no exposure to passive smoke, there was an increased risk of diabetes among nonsmokers who were occasionally (relative risk [RR] 1.10 [95% CI 0.94-1.23]) or regularly (1.16 [1.00-1.35]) exposed to passive smoke. The risk of incident type 2 diabetes was increased by 28% (12-50) among all past smokers. The risk diminished as time since quitting increased but still was elevated even 20-29 years later (1.15 [1.00-1.32]). Current smokers had the highest risk of incident type 2 diabetes in a dose-dependent manner. Adjusted RRs increased from 1.39 (1.17-1.64) for 1-14 cigarettes per day to 1.98 (1.57-2.36) for >= 25 cigarettes per day compared with nonsmokers with no exposure to passive smoke.

CONCLUSIONS-Our study suggests that exposure to passive smoke and active smoking are positively and independently associated with the risk of type 2 diabetes. Diabetes Care 34:892-897, 2011

语种英语
WOS记录号WOS:000289221800019
项目编号0535401T ; CA-87969 ; HL-079929
资助机构American Heart Association ; National Institutes of Health ; Beijing Municipal Science and Technology Commission ; International Society of Nephrology
引用统计
被引频次:54[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/50023
专题北京大学第一临床医学院_肾脏内科
作者单位1.Brigham & Womens Hosp, Dept Med, Div Renal, Boston, MA 02115 USA
2.Peking Univ, Hosp 1, Dept Med, Div Renal, Beijing 100871, Peoples R China
3.Harvard Univ, Sch Publ Hlth, Dept Nutr, Boston, MA 02115 USA
4.Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA
5.Brigham & Womens Hosp, Dept Med, Channing Lab, Boston, MA 02115 USA
6.Harvard Univ, Sch Med, Boston, MA USA
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GB/T 7714
Curhan, Gary C.,Zhang, Luxia,Hu, Frank B.,et al. Association Between Passive and Active Smoking and Incident Type 2 Diabetes in Women[J]. DIABETES CARE,2011,34(4):892-897.
APA Curhan, Gary C.,Zhang, Luxia,Hu, Frank B.,Rimm, Eric B.,&Forman, John P..(2011).Association Between Passive and Active Smoking and Incident Type 2 Diabetes in Women.DIABETES CARE,34(4),892-897.
MLA Curhan, Gary C.,et al."Association Between Passive and Active Smoking and Incident Type 2 Diabetes in Women".DIABETES CARE 34.4(2011):892-897.
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