北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 北京大学精神卫生研究所  > 期刊论文
学科主题: 精神卫生
题名:
Cross-National Analysis of the Associations among Mental Disorders and Suicidal Behavior: Findings from the WHO World Mental Health Surveys
作者: Nock, Matthew K.1; Hwang, Irving2; Sampson, Nancy2; Kessler, Ronald C.2; Angermeyer, Matthias3; Beautrais, Annette4; Borges, Guilherme5,6; Bromet, Evelyn7; Bruffaerts, Ronny8; de Girolamo, Giovanni9; de Graaf, Ron10; Florescu, Silvia11; Gureje, Oye12; Haro, Josep Maria13,14; Hu, Chiyi15,16; Huang, Yueqin17; Karam, Elie G.18,19; Kawakami, Norito20; Kovess, Viviane21; Levinson, Daphna22; Posada-Villa, Jose23; Sagar, Rajesh24; Tomov, Toma25; Viana, Maria Carmen26; Williams, David R.27
刊名: PLOS MEDICINE
发表日期: 2009-08-01
DOI: 10.1371/journal.pmed.1000123
卷: 6, 期:8
收录类别: SCI ; SSCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Medicine, General & Internal
研究领域[WOS]: General & Internal Medicine
关键词[WOS]: COMORBIDITY SURVEY REPLICATION ; POSTTRAUMATIC-STRESS-DISORDER ; PSYCHIATRIC RISK-FACTORS ; DSM-IV DISORDERS ; MAJOR DEPRESSION ; PANIC DISORDER ; PSYCHOLOGICAL AUTOPSY ; RETROSPECTIVE REPORTS ; LIFETIME PREVALENCE ; ADOLESCENT SUICIDE
英文摘要:

Background: Suicide is a leading cause of death worldwide. Mental disorders are among the strongest predictors of suicide; however, little is known about which disorders are uniquely predictive of suicidal behavior, the extent to which disorders predict suicide attempts beyond their association with suicidal thoughts, and whether these associations are similar across developed and developing countries. This study was designed to test each of these questions with a focus on nonfatal suicide attempts.

Methods and Findings: Data on the lifetime presence and age-of-onset of Diagnostic and Statistical Manual of Mental Disorders, 4th Edition (DSM-IV) mental disorders and nonfatal suicidal behaviors were collected via structured face-to-face interviews with 108,664 respondents from 21 countries participating in the WHO World Mental Health Surveys. The results show that each lifetime disorder examined significantly predicts the subsequent first onset of suicide attempt (odds ratios [ORs] = 2.9-8.9). After controlling for comorbidity, these associations decreased substantially (ORs = 1.5-5.6) but remained significant in most cases. Overall, mental disorders were equally predictive in developed and developing countries, with a key difference being that the strongest predictors of suicide attempts in developed countries were mood disorders, whereas in developing countries impulse-control, substance use, and post-traumatic stress disorders were most predictive. Disaggregation of the associations between mental disorders and nonfatal suicide attempts showed that these associations are largely due to disorders predicting the onset of suicidal thoughts rather than predicting progression from thoughts to attempts. In the few instances where mental disorders predicted the transition from suicidal thoughts to attempts, the significant disorders are characterized by anxiety and poor impulse-control. The limitations of this study include the use of retrospective self-reports of lifetime occurrence and age-of-onset of mental disorders and suicidal behaviors, as well as the narrow focus on mental disorders as predictors of nonfatal suicidal behaviors, each of which must be addressed in future studies.

Conclusions: This study found that a wide range of mental disorders increased the odds of experiencing suicide ideation. However, after controlling for psychiatric comorbidity, only disorders characterized by anxiety and poor impulse-control predict which people with suicide ideation act on such thoughts. These findings provide a more fine-grained understanding of the associations between mental disorders and subsequent suicidal behavior than previously available and indicate that mental disorders predict suicidal behaviors similarly in both developed and developing countries. Future research is needed to delineate the mechanisms through which people come to think about suicide and subsequently progress from ideation to attempts.

语种: 英语
所属项目编号: R01MH077883 ; R01MH070884 ; R13-MH066849 ; R01-MH069864 ; R01 DA016558 ; FIRCA R01-TW006481 ; QLG5-1999-01042 ; SANCO 2004123 ; FIS 00/0028 ; SAF 2000-158-CE
项目资助者: United States National Institute of Mental Health ; the Pfizer Foundation ; US Public Health Service ; Fogarty International Center ; the Pan American Health Organization ; Eli Lilly and Company ; Ortho-McNeil Pharmaceutical ; GlaxoSmithKline ; Ministry of Social Protection ; Saldarriaga Concha Foundation ; European Commission ; Piedmont Region (Italy) ; Fondo de Investigacion Sanitaria, Instituto de Salud Carlos III, Spain ; Ministerio de Ciencia y Tecnologia, Spain ; Departament de Salut, Generalitat de Catalunya, Spain
WOS记录号: WOS:000269229800011
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/50025
Appears in Collections:北京大学精神卫生研究所_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: 1.Natl Sch Publ Hlth & Hlth Serv Management, Publ Hlth Res & Evidence Based Med Dept, Bucharest, Romania
2.Harvard Univ, Dept Psychol, Cambridge, MA 02138 USA
3.Harvard Univ, Sch Med, Dept Hlth Care Policy, Boston, MA 02115 USA
4.Ctr Publ Mental Hlth, Gosing Am Wagram, Austria
5.Univ Otago, Christchurch, New Zealand
6.Natl Inst Psychiat Mexico, Dept Epidemiol Res, Div Epidemiol & Psychosocial Res, Mexico City, DF, Mexico
7.Metropolitan Autonomous Univ, Mexico City, DF, Mexico
8.SUNY Stony Brook, Dept Psychiat, Stony Brook, NY 11794 USA
9.Univ Hosp Gasthuisberg, B-3000 Louvain, Belgium
10.IRCCS, Ctr S Giovanni Dio Fatebenefratelli, Brescia, Italy
11.Netherlands Inst Mental Hlth & Addict, Utrecht, Netherlands
12.Univ Coll Ibadan Hosp, Ibadan, Nigeria
13.St Joan Deu SSM, Barcelona, Spain
14.ISCIII, Ciber Salud Mental CIBERSAM, Barcelona, Spain
15.Shenzhen Inst Mental Hlth, Shenzhen, Peoples R China
16.Shenzhen Kangning Hosp, Shenzhen, Peoples R China
17.Peking Univ, Inst Mental Hlth, Beijing 100871, Peoples R China
18.Balamand Univ, Dept Psychiat & Clin Psychol, St George Hosp Univ Med Ctr, Fac Med, Beirut, Lebanon
19.MIND, IDRAAC, Beirut, Lebanon
20.Univ Tokyo, Dept Mental Hlth, Sch Publ Hlth, Tokyo, Japan
21.Univ Paris 05, EA 4069, MGEN Fdn Publ Hlth, Paris, France
22.Mental Hlth Serv Minist Hlth, Jerusalem, Israel
23.Pontificia Univ Javeriana, Ctr Med Sabana, Bogota, Colombia
24.All India Inst Med Sci, Dept Psychiat, New Delhi, India
25.New Bulgarian Univ, Inst Human Relat, Sofia, Bulgaria
26.Univ Sao Paulo, Sch Med, Inst Psychiat, Sect Psychiat Epidemiol, Sao Paulo, Brazil
27.Harvard Univ, Sch Publ Hlth, Dept Soc Human Dev & Hlth, Boston, MA 02115 USA

Recommended Citation:
Nock, Matthew K.,Hwang, Irving,Sampson, Nancy,et al. Cross-National Analysis of the Associations among Mental Disorders and Suicidal Behavior: Findings from the WHO World Mental Health Surveys[J]. PLOS MEDICINE,2009,6(8).
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Nock, Matthew K.]'s Articles
[Hwang, Irving]'s Articles
[Sampson, Nancy]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Nock, Matthew K.]‘s Articles
[Hwang, Irving]‘s Articles
[Sampson, Nancy]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace