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学科主题: 临床医学
题名:
Clinical and electrophysiological characteristics of startle epilepsy in childhood
作者: Yang, Zhixian; Liu, Xiaoyan; Qin, Jiong; Zhang, Yuehua; Bao, Xinhua; Wang, Shuang; Chang, Xingzhi
关键词: Reflex epilepsy ; Startle ; Seizure ; Electroencephalogram
刊名: CLINICAL NEUROPHYSIOLOGY
发表日期: 2010-05-01
DOI: 10.1016/j.clinph.2009.12.020
卷: 121, 期:5, 页:658-664
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Clinical Neurology ; Neurosciences
研究领域[WOS]: Neurosciences & Neurology
关键词[WOS]: INFANTILE HEMIPLEGIA ; INDUCED SEIZURES
英文摘要:

Objective: Startle epilepsy is one syndrome of reflex epilepsies. We studied its clinical and EEG characteristics.

Methods: Analysis of the clinical and EEG characteristics of startle epilepsy.

Results: Of 11 patients, five were female. Age of onset ranged from 5 months to 7.5 years. Abnormal etiologies were found in seven patients, as a result of perinatal and postnatal factors. Neuroimaging showed abnormalities, commonly focal atrophy, in nine patients. Spontaneous seizures preceded or followed the startle seizures and were present in all patients. Startle seizures experienced included tonic, myoclonic, tonic-myoclonic, tonic-atypical absence, asymmetric tonic motor seizure and tonic-clonic seizure. Diffuse electrodecremental pattern was the most common ictal EEG pattern seen. The triggering stimuli of the startle seizures were sound in seven patients, touch in three and both sound and touch in one. Interictal EEG revealed abnormalities in 10 patients including generalized, multifocal or focal discharges. Many different anti-epileptic drugs were often unsatisfactory.

Conclusion: Startle epilepsies were often symptomatic re. ex epilepsies and there were several types of startle seizure. The ictal EEG often showed a diffuse electrodecremental pattern. This disease has a bad prognosis.

Significance: We delineated the clinical and EEG characteristics of startle epilepsy in childhood. (C) 2010 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

语种: 英语
WOS记录号: WOS:000276091300005
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/50067
Appears in Collections:北京大学第一临床医学院_儿科_期刊论文

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作者单位: Peking Univ, Dept Pediat, Hosp 1, Beijing 100034, Peoples R China

Recommended Citation:
Yang, Zhixian,Liu, Xiaoyan,Qin, Jiong,et al. Clinical and electrophysiological characteristics of startle epilepsy in childhood[J]. CLINICAL NEUROPHYSIOLOGY,2010,121(5):658-664.
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