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Clinical and electrophysiological characteristics of startle epilepsy in childhood
Yang, Zhixian; Liu, Xiaoyan; Qin, Jiong; Zhang, Yuehua; Bao, Xinhua; Wang, Shuang; Chang, Xingzhi
关键词Reflex Epilepsy Startle Seizure Electroencephalogram
刊名CLINICAL NEUROPHYSIOLOGY
2010-05-01
DOI10.1016/j.clinph.2009.12.020
121期:5页:658-664
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Clinical Neurology ; Neurosciences
研究领域[WOS]Neurosciences & Neurology
关键词[WOS]INFANTILE HEMIPLEGIA ; INDUCED SEIZURES
英文摘要

Objective: Startle epilepsy is one syndrome of reflex epilepsies. We studied its clinical and EEG characteristics.

Methods: Analysis of the clinical and EEG characteristics of startle epilepsy.

Results: Of 11 patients, five were female. Age of onset ranged from 5 months to 7.5 years. Abnormal etiologies were found in seven patients, as a result of perinatal and postnatal factors. Neuroimaging showed abnormalities, commonly focal atrophy, in nine patients. Spontaneous seizures preceded or followed the startle seizures and were present in all patients. Startle seizures experienced included tonic, myoclonic, tonic-myoclonic, tonic-atypical absence, asymmetric tonic motor seizure and tonic-clonic seizure. Diffuse electrodecremental pattern was the most common ictal EEG pattern seen. The triggering stimuli of the startle seizures were sound in seven patients, touch in three and both sound and touch in one. Interictal EEG revealed abnormalities in 10 patients including generalized, multifocal or focal discharges. Many different anti-epileptic drugs were often unsatisfactory.

Conclusion: Startle epilepsies were often symptomatic re. ex epilepsies and there were several types of startle seizure. The ictal EEG often showed a diffuse electrodecremental pattern. This disease has a bad prognosis.

Significance: We delineated the clinical and EEG characteristics of startle epilepsy in childhood. (C) 2010 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

语种英语
WOS记录号WOS:000276091300005
引用统计
被引频次:19[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/50067
专题北京大学第一临床医学院_儿科
北京大学第二临床医学院_儿科
作者单位Peking Univ, Dept Pediat, Hosp 1, Beijing 100034, Peoples R China
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GB/T 7714
Yang, Zhixian,Liu, Xiaoyan,Qin, Jiong,et al. Clinical and electrophysiological characteristics of startle epilepsy in childhood[J]. CLINICAL NEUROPHYSIOLOGY,2010,121(5):658-664.
APA Yang, Zhixian.,Liu, Xiaoyan.,Qin, Jiong.,Zhang, Yuehua.,Bao, Xinhua.,...&Chang, Xingzhi.(2010).Clinical and electrophysiological characteristics of startle epilepsy in childhood.CLINICAL NEUROPHYSIOLOGY,121(5),658-664.
MLA Yang, Zhixian,et al."Clinical and electrophysiological characteristics of startle epilepsy in childhood".CLINICAL NEUROPHYSIOLOGY 121.5(2010):658-664.
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