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学科主题: 临床医学
题名:
Arterial stiffness is increased in healthy subjects with a positive family history of hypertension
作者: Liu, Jinbo; Wang, Hongyu; Zhao, Hongwei; Liu, Huan; Li, Lihong; Zhou, Yingyan
关键词: Arterial stiffness ; arteriosclerosis ; family history ; hypertension ; pulse wave velocity
刊名: CLINICAL AND EXPERIMENTAL HYPERTENSION
发表日期: 2015-11-17
DOI: 10.3109/10641963.2015.1036061
卷: 37, 期:8, 页:622-626
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Pharmacology & Pharmacy ; Peripheral Vascular Disease
研究领域[WOS]: Pharmacology & Pharmacy ; Cardiovascular System & Cardiology
关键词[WOS]: PULSE-WAVE VELOCITY ; CORONARY-HEART-DISEASE ; POPULATION ; ATHEROSCLEROSIS
英文摘要:

A positive family history of hypertension is a risk factor for cardiovascular diseases. We investigated the value of pulse wave velocity (PWV) in healthy subjects with a positive family history of hypertension. 255 healthy subjects (M/F: 75/180) were divided into two groups according to without (group 1) or with (group 2) a positive family history of hypertension. Carotid-femoral pulse wave velocity (CF-PWV) was measured by Complior apparatus. Our results showed that CF-PWV was significantly higher in group 2 than in group 1 (7.90 +/- 1.31 versus 7.32 +/- 1.15m/s, p<0.001). High-density lipoprotein cholesterol (HDL-C) was significantly higher in group 1 than in group 2. Multiple linear regressions showed that age, family history, GLU, and MAP were independent influencing factors of CF-PWV in the entire study group. Our present study showed PWV is significantly higher in healthy subjects with a positive family history of hypertension. Family history might play an important role in this process.

语种: 英语
所属项目编号: 2011-4026-02 ; 2010-Y002 ; 2014-Hospital-Clinical-02 ; 2012Y04 ; 2013 Keguan 20-1 ; 2014-ME-07
项目资助者: Capital Health Research and Development of Special ; Hospital Fund of Peking University Shougang Hospital ; Shougang Keji Fund ; Seeding Grant for Medicine and Engineering Sciences of Peking University
WOS记录号: WOS:000364482900003
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/50090
Appears in Collections:北京大学首钢医院_心血管内科_期刊论文

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作者单位: Peking Univ, Shougang Hosp, Dept Vasc Med, Beijing 100144, Peoples R China

Recommended Citation:
Liu, Jinbo,Wang, Hongyu,Zhao, Hongwei,et al. Arterial stiffness is increased in healthy subjects with a positive family history of hypertension[J]. CLINICAL AND EXPERIMENTAL HYPERTENSION,2015,37(8):622-626.
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