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学科主题临床医学
Differential diagnosis of non-functional islet cell tumor and pancreatic carcinoma with sonography
Yang, Wei; Chen, Min-Hua; Yan, Kun; Wu, Wei; Dai, Ying; Zhang, Hui
关键词Non-functional Islet Cell Tumor Pancreatic Ductal Adenocarcinoma Endocrinology Ultrasound Contrast Enhanced Ultrasound
刊名EUROPEAN JOURNAL OF RADIOLOGY
2007-06-01
DOI10.1016/j.ejrad.2007.02.042
62期:3页:342-351
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Radiology, Nuclear Medicine & Medical Imaging
研究领域[WOS]Radiology, Nuclear Medicine & Medical Imaging
关键词[WOS]ENDOCRINE TUMORS ; PATHOLOGICAL CORRELATION ; COMPUTED-TOMOGRAPHY ; DYNAMIC CT ; ULTRASONOGRAPHY
英文摘要

Objective: To investigate the differential diagnosis of non-functional islet cell tumor (NFICT) and pancreatic ductal adenocarcinoma (pancreatic carcinoma) with clinical presentation and sonographic features.

Materials and methods: Twenty cases of NFICT were investigated in the study, and 41 cases of pancreatic carcinoma were included as the control group. Among them, 5 NFICT and 32 pancreatic carcinomas underwent CEUS with SonoVue. Clinical presentation and sonographic characteristics were evaluated with Logistic regression analysis. Furthermore, the preliminary result of contrast enhanced ultrasound (CEUS) was analyzed.

Results: Statistic analysis showed four significant factors in differential diagnosis for NFICT and pancreatic carcinoma, including age (P < 0.001), tumor size (P = 0.006), tumor margin (P < 0.001) and vascularity of tumor (P = 0.004). Combined these four factors, the sensitivity, specificity and accuracy are 95.0%, 95.1% and 95.1%, respectively. When the patient is younger than 60 years, and tumor is smaller than 5 cm with well-defined margin and hypervascular, it would be most likely a NFICT other than pancreatic carcinoma. NFICT often shows early enhancement and more homogeneous infusion than pancreatic carcinoma on CEUS (P = 0.005 and 0.008).

Conclusions: Sonography is able to provide useful differential information for NFICT, which is often misdiagnosed as pancreatic carcinoma. (C) 2007 Elsevier Ireland Ltd. All rights reserved.

语种英语
WOS记录号WOS:000247801200005
引用统计
被引频次:21[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/50115
专题北京大学临床肿瘤学院_超声科
作者单位Peking Univ, Sch Oncol, Dept Ultrasound, Beijing 100036, Peoples R China
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Yang, Wei,Chen, Min-Hua,Yan, Kun,et al. Differential diagnosis of non-functional islet cell tumor and pancreatic carcinoma with sonography[J]. EUROPEAN JOURNAL OF RADIOLOGY,2007,62(3):342-351.
APA Yang, Wei,Chen, Min-Hua,Yan, Kun,Wu, Wei,Dai, Ying,&Zhang, Hui.(2007).Differential diagnosis of non-functional islet cell tumor and pancreatic carcinoma with sonography.EUROPEAN JOURNAL OF RADIOLOGY,62(3),342-351.
MLA Yang, Wei,et al."Differential diagnosis of non-functional islet cell tumor and pancreatic carcinoma with sonography".EUROPEAN JOURNAL OF RADIOLOGY 62.3(2007):342-351.
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