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学科主题: 临床医学
题名:
Differential diagnosis of non-functional islet cell tumor and pancreatic carcinoma with sonography
作者: Yang, Wei; Chen, Min-Hua; Yan, Kun; Wu, Wei; Dai, Ying; Zhang, Hui
关键词: non-functional islet cell tumor ; pancreatic ductal adenocarcinoma ; endocrinology ; ultrasound ; contrast enhanced ultrasound
刊名: EUROPEAN JOURNAL OF RADIOLOGY
发表日期: 2007-06-01
DOI: 10.1016/j.ejrad.2007.02.042
卷: 62, 期:3, 页:342-351
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Radiology, Nuclear Medicine & Medical Imaging
研究领域[WOS]: Radiology, Nuclear Medicine & Medical Imaging
关键词[WOS]: ENDOCRINE TUMORS ; PATHOLOGICAL CORRELATION ; COMPUTED-TOMOGRAPHY ; DYNAMIC CT ; ULTRASONOGRAPHY
英文摘要:

Objective: To investigate the differential diagnosis of non-functional islet cell tumor (NFICT) and pancreatic ductal adenocarcinoma (pancreatic carcinoma) with clinical presentation and sonographic features.

Materials and methods: Twenty cases of NFICT were investigated in the study, and 41 cases of pancreatic carcinoma were included as the control group. Among them, 5 NFICT and 32 pancreatic carcinomas underwent CEUS with SonoVue. Clinical presentation and sonographic characteristics were evaluated with Logistic regression analysis. Furthermore, the preliminary result of contrast enhanced ultrasound (CEUS) was analyzed.

Results: Statistic analysis showed four significant factors in differential diagnosis for NFICT and pancreatic carcinoma, including age (P < 0.001), tumor size (P = 0.006), tumor margin (P < 0.001) and vascularity of tumor (P = 0.004). Combined these four factors, the sensitivity, specificity and accuracy are 95.0%, 95.1% and 95.1%, respectively. When the patient is younger than 60 years, and tumor is smaller than 5 cm with well-defined margin and hypervascular, it would be most likely a NFICT other than pancreatic carcinoma. NFICT often shows early enhancement and more homogeneous infusion than pancreatic carcinoma on CEUS (P = 0.005 and 0.008).

Conclusions: Sonography is able to provide useful differential information for NFICT, which is often misdiagnosed as pancreatic carcinoma. (C) 2007 Elsevier Ireland Ltd. All rights reserved.

语种: 英语
WOS记录号: WOS:000247801200005
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/50115
Appears in Collections:北京大学临床肿瘤学院_超声科_期刊论文

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作者单位: Peking Univ, Sch Oncol, Dept Ultrasound, Beijing 100036, Peoples R China

Recommended Citation:
Yang, Wei,Chen, Min-Hua,Yan, Kun,et al. Differential diagnosis of non-functional islet cell tumor and pancreatic carcinoma with sonography[J]. EUROPEAN JOURNAL OF RADIOLOGY,2007,62(3):342-351.
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