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学科主题临床医学
Development of a Biomedical Micro/Nano Robot for Drug Delivery
Zhang, Zhenhai1; Li, Zhifei2; Yu, Wei3; Li, Kejie1; Xie, Zhihong4
关键词Micro/nano Robot Bacterial Flagellar Motor Liposome Antibody Drug Delivery System
刊名JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
2015-04-01
DOI10.1166/jnn.2015.9643
15期:4页:3126-3129
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Chemistry, Multidisciplinary ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied ; Physics, Condensed Matter
研究领域[WOS]Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics
关键词[WOS]FLAGELLA ; MOTOR
英文摘要

Flagellated bacteria have been utilized as potential swimming micro-robotic bodies for propulsion of spherical liposome by attaching several bacteria on their surface. Liposome as a drug delivery vehicle can contain biologically active compounds. In this work, the antibody binding technique is developed to attach bacteria to liposome′s surface. Consequently, the stochastic effect of bacterial propulsion of liposome is investigated analytically and experimentally. It is shown that the mobility of liposome with bacteria was higher than that of liposome without bacteria. Experimental data matches well with statistical calculation.

语种英语
WOS记录号WOS:000347435100080
项目编号61273346 ; 31370108 ; 51106093 ; 50876058 ; 1103000003 ; 2013JH021 ; C x x 20110003 ; A x x 20110005 ; A x x 20132010 ; 20121101120009 ; 2012YG0203 ; 2013CX04031 ; 2011CX02023 ; 2014CX x x x x ; B08043
资助机构National Natural Science Foundation of China ; Hundred Talents Program of Chinese Academy of Sciences ; Key Projects in the Yantai Science and Technology Pillar Program ; National Defense Major Fundamental Research Program of China ; National Defense Key Fundamental Research Program of China ; Specialized Research Fund for the Doctoral Program of Higher Education ; Scientific Research Foundation for the Returned Overseas Chinese Scholars, Excellent Young Scholars Research Fund of Beijing Institute of Technology ; Program for the Fundamental Research of Beijing Institute of Technology ; Program of Introducing Talents of Discipline to University, China
引用统计
被引频次:1[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/50140
专题北京大学第三临床医学院_普通外科
作者单位1.Beijing Inst Technol, Sch Mechatron Engn, Beijing 100081, Peoples R China
2.Peking Univ, Dept Gen Surg, Hosp 3, Beijing 100191, Peoples R China
3.Shanghai Second Polytech Univ, Sch Urban Dev & Environm Engn, Shanghai 201209, Peoples R China
4.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Shandong, Peoples R China
推荐引用方式
GB/T 7714
Zhang, Zhenhai,Li, Zhifei,Yu, Wei,et al. Development of a Biomedical Micro/Nano Robot for Drug Delivery[J]. JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY,2015,15(4):3126-3129.
APA Zhang, Zhenhai,Li, Zhifei,Yu, Wei,Li, Kejie,&Xie, Zhihong.(2015).Development of a Biomedical Micro/Nano Robot for Drug Delivery.JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY,15(4),3126-3129.
MLA Zhang, Zhenhai,et al."Development of a Biomedical Micro/Nano Robot for Drug Delivery".JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY 15.4(2015):3126-3129.
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