IR@PKUHSC  > 北京大学药学院
学科主题药学
High-performance liquid chromatographic assay for the active saponins from Panax notoginseng in rat tissues
Zhang, JL1; Li, L1; Sheng, YX1; Wang, SS1; Guo, DA1
关键词Panax Notoginseng Ginsenosides Tissue Distribution Pharmacokinetics
刊名BIOMEDICAL CHROMATOGRAPHY
2006-04-01
DOI10.1002/bmc.567
20期:4页:327-335
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Biochemical Research Methods ; Biochemistry & Molecular Biology ; Chemistry, Analytical ; Pharmacology & Pharmacy
研究领域[WOS]Biochemistry & Molecular Biology ; Chemistry ; Pharmacology & Pharmacy
关键词[WOS]GINSENG SAPONINS ; METABOLISM ; ABSORPTION ; EXCRETION ; RG(1) ; RB-1 ; RG1
英文摘要

A reversed-phase liquid chromatographic method was used to determine the ginsenosides Rg(1), Rb-1 and Rd of Panax notoginseng in rat tissues (kidney, liver, heart, spleen and lung) after the administration of total saponins of P. notoginseng. The tissue samples were treated with solid-phase extraction prior to HPLC. The calibration curves for the three saponins were linear in the given concentration ranges. The intra-day and inter-day assay coefficients in tissues were between 76 and 120% respectively. The recoveries of all the tissues were higher than 70%. This method was applied to evaluate the distribution of the three major saponins of P. notoginseng in rat tissues. Copyright (c) 2005 John Wiley & Sons, Ltd.

语种英语
WOS记录号WOS:000237238200004
引用统计
被引频次:26[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/50169
专题北京大学药学院
北京大学第一临床医学院_医疗耗材科
北京大学口腔医学院_口腔预防保健科
作者单位1.Peking Univ, Sch Pharmaceut Sci, Beijing 100083, Peoples R China
2.Peking Univ, Modern Res Ctr Tradit Chinese Med, Beijing 100083, Peoples R China
推荐引用方式
GB/T 7714
Zhang, JL,Li, L,Sheng, YX,et al. High-performance liquid chromatographic assay for the active saponins from Panax notoginseng in rat tissues[J]. BIOMEDICAL CHROMATOGRAPHY,2006,20(4):327-335.
APA Zhang, JL,Li, L,Sheng, YX,Wang, SS,&Guo, DA.(2006).High-performance liquid chromatographic assay for the active saponins from Panax notoginseng in rat tissues.BIOMEDICAL CHROMATOGRAPHY,20(4),327-335.
MLA Zhang, JL,et al."High-performance liquid chromatographic assay for the active saponins from Panax notoginseng in rat tissues".BIOMEDICAL CHROMATOGRAPHY 20.4(2006):327-335.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Zhang, JL]的文章
[Li, L]的文章
[Sheng, YX]的文章
百度学术
百度学术中相似的文章
[Zhang, JL]的文章
[Li, L]的文章
[Sheng, YX]的文章
必应学术
必应学术中相似的文章
[Zhang, JL]的文章
[Li, L]的文章
[Sheng, YX]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。