|Underlying diseases in syncope of children in China|
|Chen Li1; Wang Cheng2; Wang Hongwei3; Tian Hong4; Tang Chaoshu5,6; Jin Hongfang1; Du Junbao1|
|关键词||Children Syncope Neurally-mediated Syncope|
|刊名||MEDICAL SCIENCE MONITOR|
|WOS标题词||Science & Technology|
|类目[WOS]||Medicine, Research & Experimental|
|研究领域[WOS]||Research & Experimental Medicine|
|关键词[WOS]||OF-CARDIOLOGY ; CARE ; STATEMENT ; SOCIETY|
Background: Syncope accounts for about 1-2% of emergency department visits, but the etiology in many patients with syncope is unclear. Recently, with the use of the head-up tilt test (HUT), the number of patients with unexplained syncope (UPS) has been decreasing; however, the spectrum of underlying diseases of syncope in children is unclear. This retrospective study aimed to analyze the spectrum of underlying diseases in children with syncope.
Material/Methods: This multi-center clinical study consisted of 888 children (417 males, 471 females, aged 5-18 yrs, median age 12.0 +/- 3.0 yrs) with syncope who came from Beijing city, Hunan province, Hubei province and Shanghai from August 1999 to March 2009. The clinical and laboratory data of children were studied and the spectrum of underlying diseases in children with syncope was analyzed.
Results: In 888 children with syncope, 175 (19.7%) had vasovagal syncope (VVS) with vasoinhibitory response, 35 (3.9%) had VVS with cardioinhibitory response, 73 (8.2%) had VVS with mixed response, 286 (32.2%) had postural orthostatic tachycardia syndrome (POTS), 19 (2.1%) had orthostatic hypotension, 7 (0.9%) had situational syncope, 13 (1.5%) had cardiogenic syncope, and 280 (31.5%) had unexplained syncope.
Conclusions: The data suggest that neurally-mediated syncope was the most common cause in children with syncope. POTS and VVS were the most common hemodynamic patterns of neurally-mediated syncope.
|资助机构||Capital Medical Development Scientific Project ; Science and Technology Program of Beijing ; Changjiang Scholar Program|
|作者单位||1.Fudan Univ Pediat Hosp, Dept Electrocardiogram, Shanghai, Peoples R China|
2.Peking Univ 1st Hosp, Dept Pediat, Beijing 100034, Peoples R China
3.Zhongnan Univ Xiangya 2nd Hosp, Dept Pediat, Changsha, Hunan, Peoples R China
4.Huazhong Univ Sci & Technol, Tongji Med Coll, Dept Pediat, Wuhan, Hubei Province, Peoples R China
5.Peking Univ Hlth Sci Ctr, Beijing, Peoples R China
6.Minist Educ, Key Lab Mol Cardiovasc Med, Beijing, Peoples R China
|Chen Li,Wang Cheng,Wang Hongwei,et al. Underlying diseases in syncope of children in China[J]. MEDICAL SCIENCE MONITOR,2011,17(6):PH49-PH53.|
|APA||Chen Li.,Wang Cheng.,Wang Hongwei.,Tian Hong.,Tang Chaoshu.,...&Du Junbao.(2011).Underlying diseases in syncope of children in China.MEDICAL SCIENCE MONITOR,17(6),PH49-PH53.|
|MLA||Chen Li,et al."Underlying diseases in syncope of children in China".MEDICAL SCIENCE MONITOR 17.6(2011):PH49-PH53.|