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学科主题基础医学
Modulation of cold pain in human brain by electric acupoint stimulation: evidence from fMRI
Zhang, WT1; Jin, Z1; Huang, J1; Zhang, L1; Zeng, YW1; Luo, F1; Chen, ACN1; Han, JS1
关键词acupuncture analgesia anterior cingulate cortex fMRI pain somatosensory area
刊名NEUROREPORT
2003-08-26
DOI10.1097/01.wnr.0000085243.71403.6a
14期:12页:1591-1596
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Neurosciences
研究领域[WOS]Neurosciences & Neurology
关键词[WOS]ELECTROACUPUNCTURE STIMULATION ; ACUPUNCTURE STIMULATION ; DIFFERENT FREQUENCIES ; ACTIVATION ; ANALGESIA ; PATTERNS ; POINT ; GRAY ; HEAT
英文摘要

The purpose of this study is to investigate the modulation of pain responses in the human brain by electric acupoint stimulation (EAS). Eight healthy subjects were enrolled; each received real or mock EAS treatment in separate sessions. Cool (18degreesC) and cold (2degreesC) stimuli were delivered, during which functional magnetic resonance imaging scans were performed, before and after treatment. Real EAS specifically increased the pain-specific activation in bilateral secondary somatosensory area, medial prefrontal cortex, and Brodmann area (BA) 32, while it decreased the activation in contralateral primary somatosensory area, BA7, and BA24. We suggest that EAS may induce an analgesic effect via modulation of both the sensory and the emotional aspect of pain processing.

语种英语
WOS记录号WOS:000185293800010
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被引频次:39[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
版本出版稿
条目标识符http://ir.bjmu.edu.cn/handle/400002259/50217
专题北京大学基础医学院_神经生物学系
北京大学基础医学院
作者单位1.Peking Univ, Dept Neurobiol, Beijing 100083, Peoples R China
2.Hosp 306, Dept Radiol, Beijing 100101, Peoples R China
3.Hosp 306, fMRI Ctr, Beijing 100101, Peoples R China
4.Univ Aalborg, Human Brain Mapping & Cort Imaging Lab, Aalborg, Denmark
推荐引用方式
GB/T 7714
Zhang, WT,Jin, Z,Huang, J,et al. Modulation of cold pain in human brain by electric acupoint stimulation: evidence from fMRI[J]. NEUROREPORT,2003,14(12):1591-1596.
APA Zhang, WT.,Jin, Z.,Huang, J.,Zhang, L.,Zeng, YW.,...&Han, JS.(2003).Modulation of cold pain in human brain by electric acupoint stimulation: evidence from fMRI.NEUROREPORT,14(12),1591-1596.
MLA Zhang, WT,et al."Modulation of cold pain in human brain by electric acupoint stimulation: evidence from fMRI".NEUROREPORT 14.12(2003):1591-1596.
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