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学科主题: 医学信息学
题名:
Improved survival among patients with base of tongue and tonsil cancer in the United States
作者: Yu, Guo-Pei1,2,3,4; Mehta, Vikas1,3; Branovan, Daniel1,3; Huang, Qiang1,3; Hashibe, Mia5; Zhang, Zuo-Feng6; Schantz, Stimson P.1,3
关键词: Base of tongue cancer ; Tonsil cancer ; Survival ; Time trend ; HPV
刊名: CANCER CAUSES & CONTROL
发表日期: 2012
DOI: 10.1007/s10552-011-9864-y
卷: 23, 期:1, 页:153-164
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Oncology ; Public, Environmental & Occupational Health
研究领域[WOS]: Oncology ; Public, Environmental & Occupational Health
关键词[WOS]: SQUAMOUS-CELL CARCINOMA ; HUMAN-PAPILLOMAVIRUS INFECTION ; ORAL-CANCER ; NECK-CANCER ; OROPHARYNGEAL CARCINOMA ; PROGNOSTIC-FACTOR ; RANDOMIZED TRIAL ; INCIDENCE TRENDS ; US POPULATION ; HEAD
英文摘要:

To examine if survival has changed over the last 20 years in patients with base of tongue and tonsil cancers in the United States.

Using SEER data, we employed Kaplan-Meier method to draw survival curves and calculate survival rates, and estimated adjusted hazard ratios (HR).

From the 1980s to the 2000s, the 5-year overall survival rates statistically significantly improved by 100% from 25 to 51% among patients with one primary base of tongue cancer and 28-60% among those with one primary tonsil cancer (p values for trend < 0.001). In addition, the 5-year cancer-specific survival improved by 222.4 and 276%, respectively, among two types of patients. Survival improvement was more pronounced among male patients than among female patients regardless of young or old age, while the improvement was generally consistent among patients with different tumor stages and treatment methods. In contrast, however, those patients with subsequent multiple cancers showed no improvement in overall survival over time.

The survival of patients with base of tongue and tonsil cancer has significantly improved over the last decades in the United States. Whether the improvement is associated with HPV infection, screening, or early detection is worthy to study in future.

语种: 英语
WOS记录号: WOS:000297757400015
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/50254
Appears in Collections:北京大学医学信息学中心_期刊论文

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作者单位: 1.Univ Calif Los Angeles, Sch Publ Hlth, Dept Epidemiol, Los Angeles, CA 90095 USA
2.New York Eye & Ear Infirm, Dept Otolaryngol, New York, NY 10003 USA
3.New York Eye & Ear Infirm, Biostat & Epidemiol Serv, New York, NY 10003 USA
4.New York Med Coll, Valhalla, NY 10595 USA
5.Peking Univ, Med Informat Ctr, Beijing 100191, Peoples R China
6.Univ Utah, Sch Med, Div Publ Hlth, Salt Lake City, UT 84018 USA

Recommended Citation:
Yu, Guo-Pei,Mehta, Vikas,Branovan, Daniel,et al. Improved survival among patients with base of tongue and tonsil cancer in the United States[J]. CANCER CAUSES &amp; CONTROL,2012,23(1):153-164.
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