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学科主题: 临床医学
题名:
Ultrasound Biomicroscopic Features Associated with Angle Closure in Fellow Eyes of Acute Primary Angle Closure after Laser Iridotomy
作者: Yao, Bao-qun1,2; Wu, Ling-ling1; Zhang, Chun1; Wang, Xin1
刊名: OPHTHALMOLOGY
发表日期: 2009-03-01
DOI: 10.1016/j.ophtha.2008.10.019
卷: 116, 期:3, 页:444-448
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Ophthalmology
研究领域[WOS]: Ophthalmology
关键词[WOS]: PERIPHERAL IRIDOTOMY ; LIWAN EYE ; GLAUCOMA ; OUTCOMES ; PROVOCATION ; PREVALENCE ; IRIDECTOMY ; MECHANISM
英文摘要:

Purpose: To investigate the frequency of appositional angle closure and related anatomic characteristics in fellow eyes of Chinese subjects with acute primary angle closure (APAC) after laser peripheral iridotomy (LPI).

Design: Cross-sectional study.

Participants: Consecutive subjects with APAC presenting from April 2006 to September 2006 at the Glaucoma Service of Peking University Eye Center, Peking University Third Hospital.

Methods: Under dark conditions, fellow eyes were divided into 2 groups based on the detection of appositional angle closure by ultrasound biomicroscopy (UBM). For all subjects, UBM parameters were measured to evaluate the different anatomic features between the 2 groups. Darkroom provocative tests (DRPTs) and gonioscopy were performed to investigate the relationship between angle closure and intraocular pressure.

Main Outcome Measures: Central anterior chamber depth (ACD); angle opening distance(500) (AOD(500)); angle recess area(750) (ARA(750)); trabecular-iris angle (T-I angle); trabecular-ciliary process distance (TCPD); peripheral iris thickness (IT(1)); iris-zonule distance (IZD); and the position of the iris insertion.

Results: Thirty-four post-LPI fellow eyes of 34 patients with APAC (8 men, 26 women; mean +/- standard deviation age 66.3 +/- 7.2 years, range 54-83) were included. Peripheral anterior synechiae (PAS) were not observed in any subject. Appositional angle closure was observed in at least 1 quadrant in 13 (38.2%) of the 34 patients. Compared with eyes without appositional closure, eyes with appositional closure showed significantly lower AOD(500), ARA(750), and T-I angle in 4 quadrants; shorter TCPD in the inferior and temporal quadrants; and thicker IT(1) in the superior and nasal quadrants (P<0.05). The DRPT results were positive in 3 (11.1%) of 27 eyes with appositional closure in 0 to 2 quadrants and in 3 (75.0%) of 4 eyes with appositional closure in 3 to 4 quadrants (P = 0.0164).

Conclusions: Under dark conditions, more than one third of fellow eyes of APAC showed appositional angle closure after LPI. The anatomic findings indicate a narrower angle, a more anterior position of the ciliary body, and a thicker peripheral iris in fellow eyes of APAC after LPI may be associated with an increased risk for progressive angle closure.

Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article. Ophthalmology 2009;116:444-448 (C) 2009 by the American Academy of Ophthalmology.

语种: 英语
WOS记录号: WOS:000264005400013
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/50273
Appears in Collections:北京大学第三临床医学院_眼科_期刊论文

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作者单位: 1.Tianjin Med Univ, Gen Hosp, Dept Ophthalmol, Tianjin, Peoples R China
2.Peking Univ, Hosp 3, Ctr Eye, Beijing 100083, Peoples R China

Recommended Citation:
Yao, Bao-qun,Wu, Ling-ling,Zhang, Chun,et al. Ultrasound Biomicroscopic Features Associated with Angle Closure in Fellow Eyes of Acute Primary Angle Closure after Laser Iridotomy[J]. OPHTHALMOLOGY,2009,116(3):444-448.
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