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学科主题: 临床医学
题名:
Application and Performance of Two Stroke Outcome Prediction Models in a Chinese Population
作者: Li, Wen-Juan; Gao, Zhi-Yu; He, Yang; Liu, Guang-Zhi; Gao, Xu-Guang
刊名: PM&R
发表日期: 2012-02-01
DOI: 10.1016/j.pmrj.2011.08.669
卷: 4, 期:2, 页:123-128
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Rehabilitation ; Sport Sciences
研究领域[WOS]: Rehabilitation ; Sport Sciences
关键词[WOS]: HYPER-ACUTE STROKE ; ISCHEMIC-STROKE ; SCALE SCORE ; VALIDATION ; TRIAL ; ROC
英文摘要:

Objective: To apply and examine the performance of 2 acute stroke outcome prediction models, the Six Simple Variable Model (SSV model) and the One-Year Mortality Model (OYM model), in patients in China who had either a cerebral infarction or a cerebral hemorrhage.

Design: An observational study that used both retrospective and prospective study methods.

Setting: A regional acute care facility in China.

Participants: Two hundred and forty-eight consecutive patients who had an acute stroke who were admitted to the hospital between October 2007 and March 2009.

Interventions: Not applicable.

Main Outcome Measures: Survival and daily activity independence 6 months after a stroke and 1-year mortality.

Results: The study sample had a mean age of 68.6 years (standard deviation, 11.1); 52.8% of the subjects were men, 66.5% had a cerebral infarction, and 33.5% had a cerebral hemorrhage. In the cohort, 107 patients (43.1%) achieved daily activity independence at 6-month follow-up, and 52 patients (21.0%) had died within 1 year. The area under the receiver operating characteristic curve (ROC) was 0.966 (0.935-0.998) for patients who had a cerebral infarction and 0.859 (0.766-0.952) for patients who had a cerebral hemorrhage in the prediction of 6-month survival and daily activity independence with use of the SSV model. The area under the ROC curve was 0.894 (0.846-0.965) for patients who had a cerebral infarction and 0.937 (0.904-0.988) for patients who had a cerebral hemorrhage in the prediction of 1-year mortality when the OYM model was used.

Conclusions: Both the SSV and OYM prognostic models can be used for function and mortality outcome prediction for patients in China who have had a stroke. Variation existed in the precision of prediction between patients who had a cerebral infarction and those who had a cerebral hemorrhage. Other potential factors influencing functional recovery and mortality after stroke must be considered in outcome prediction.

语种: 英语
WOS记录号: WOS:000305438300006
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/50311
Appears in Collections:北京大学第二临床医学院_神经内科_期刊论文

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作者单位: Peking Univ Peoples Hosp, Dept Neurol, Beijing 100044, Peoples R China

Recommended Citation:
Li, Wen-Juan,Gao, Zhi-Yu,He, Yang,et al. Application and Performance of Two Stroke Outcome Prediction Models in a Chinese Population[J]. PM&R,2012,4(2):123-128.
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