|Impact of Individual and Environmental Socioeconomic Status on Peritoneal Dialysis Outcomes: A Retrospective Multicenter Cohort Study|
|Xu, Rong1; Han, Qing-Feng2; Zhu, Tong-Ying3; Ren, Ye-Ping4; Chen, Jiang-Hua5; Zhao, Hui-Ping6; Chen, Meng-Hua7; Dong, Jie1; Wang, Yue2; Hao, Chuan-Ming3; Zhang, Rui4; Zhang, Xiao-Hui5; Wang, Mei6; Tian, Na7; Wang, Hai-Yan1|
|WOS标题词||Science & Technology|
|研究领域[WOS]||Science & Technology - Other Topics|
|关键词[WOS]||CHRONIC KIDNEY-DISEASE ; TECHNIQUE FAILURE ; SURVIVAL ; HEMODIALYSIS ; MORTALITY ; PATIENT ; RISK ; POPULATION ; PREDICTORS ; HEALTH|
Objectives: We aimed to explore the impacts of individual and environmental socioeconomic status (SES) on the outcome of peritoneal dialysis (PD) in regions with significant SES disparity, through a retrospective multicenter cohort in China.
Methods: Overall, 2,171 incident patients from seven PD centers were included. Individual SES was evaluated from yearly household income per person and education level. Environmental SES was represented by regional gross domestic product (GDP) per capita and medical resources. Undeveloped regions were defined as those with regional GDP lower than the median. All-cause and cardiovascular death and initial peritonitis were recorded as outcome events.
Results: Poorer PD patients or those who lived in undeveloped areas were younger and less-educated and bore a heavier burden of medical expenses. They had lower hemoglobin and serum albumin at baseline. Low income independently predicted the highest risks for all-cause or cardiovascular death and initial peritonitis compared with medium and high income. The interaction effect between individual education and regional GDP was determined. In undeveloped regions, patients with an elementary school education or lower were at significantly higher risk for all-cause death but not cardiovascular death or initial peritonitis compared with those who attended high school or had a higher diploma. Regional GDP was not associated with any outcome events.
Conclusion: Low personal income independently influenced all-cause and cardiovascular death, and initial peritonitis in PD patients. Education level predicted all-cause death only for patients in undeveloped regions. For PD patients in these high risk situations, integrated care before dialysis and well-constructed PD training programs might be helpful.
|作者单位||1.Peking Univ, Dept Nephrol, Hosp 3, Beijing 100871, Peoples R China|
2.Peking Univ, Key Lab Renal Dis, Minist Educ,Hosp 1, Renal Div,Dept Med,Inst Nephrol,Minist Hlth, Beijing 100871, Peoples R China
3.Fudan Univ, Dept Nephrol, Huashan Hosp, Shanghai 200433, Peoples R China
4.Harbin Med Univ, Affiliated Hosp 2, Dept Nephrol, Harbin, Heilongjiang, Peoples R China
5.Zhejiang Univ, Coll Med, Affiliated Hosp 1, Kidney Dis Ctr, Hangzhou 310003, Zhejiang, Peoples R China
6.Peking Univ, Dept Nephrol, Peoples Hosp, Beijing 100871, Peoples R China
7.Ningxia Med Univ, Gen Hosp, Dept Nephrol, Ningxia, Peoples R China
|Xu, Rong,Han, Qing-Feng,Zhu, Tong-Ying,et al. Impact of Individual and Environmental Socioeconomic Status on Peritoneal Dialysis Outcomes: A Retrospective Multicenter Cohort Study[J]. PLOS ONE,2012,7(11).|
|APA||Xu, Rong.,Han, Qing-Feng.,Zhu, Tong-Ying.,Ren, Ye-Ping.,Chen, Jiang-Hua.,...&Wang, Hai-Yan.(2012).Impact of Individual and Environmental Socioeconomic Status on Peritoneal Dialysis Outcomes: A Retrospective Multicenter Cohort Study.PLOS ONE,7(11).|
|MLA||Xu, Rong,et al."Impact of Individual and Environmental Socioeconomic Status on Peritoneal Dialysis Outcomes: A Retrospective Multicenter Cohort Study".PLOS ONE 7.11(2012).|