IR@PKUHSC  > 北京大学精神卫生研究所
学科主题精神卫生
Family-based association study of markers on chromosome 22 in schizophrenia using African-American, European-American, and Chinese families
Takahashi, S1; Cui, YH1; Kojima, T1; Han, YH1; Zhou, RL1; Kamioka, M1; Yu, SY1; Matsuura, M1; Matsushima, E1; Wilcox, M1; Arinami, T1; Shen, YC1; Faraone, SV1; Tsuang, MT1
关键词Schizophrenia Chromosome 22 D22s683 Family-based Association Study Fbat
刊名AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS
2003-07-01
DOI10.1002/ajmg.b.20031
120B期:1页:11-17
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Genetics & Heredity ; Psychiatry
研究领域[WOS]Genetics & Heredity ; Psychiatry
关键词[WOS]CARDIO-FACIAL SYNDROME ; GENOME-WIDE SEARCH ; SUSCEPTIBILITY LOCUS ; TRANSMISSION DISEQUILIBRIUM ; MILLENNIUM-CONSORTIUM ; UNIFIED APPROACH ; LINKAGE ANALYSIS ; GENES ; D22S278 ; TESTS
英文摘要

Several studies suggest that loci at chromosome 22q11.2-q13 might be linked to susceptibility to schizophrenia. Here we performed family-based association studies on chromosome 22q using 12 DNA microsatellite markers in African-American, European-American, and Chinese pedigrees. The marker D22S683 showed significant linkage and association with schizophrenia in not only the European-American sample but also in a combined sample (European-American and Chinese samples). Notably, D22S683 is located nearby and between D22S278 and D22S283, which have shown linkage and association to schizophrenia in prior reports. However, we found no significant association for the African-American sample. In conclusion, our data provide further support for the idea that the region around D22S683 contains a susceptibility gene for schizophrenia. (C) 2003 Wiley-Liss, Inc.

语种英语
WOS记录号WOS:000183711300002
引用统计
被引频次:24[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/50404
专题北京大学精神卫生研究所
作者单位1.Harvard Univ, Sch Med, Dept Psychiat, Massachusetts Mental Hlth Ctr, Boston, MA 02115 USA
2.Nihon Univ, Sch Med, Dept Neuropsychiat, Tokyo, Japan
3.Beijing Med Univ, Inst Mental Hlth, Beijing 100083, Peoples R China
4.Univ Tsukuba, Inst Basic Med Sci, Dept Med Genet, Tsukuba, Ibaraki 305, Japan
5.Tokyo Med & Dent Univ, Fac Med, Dept Neuropsychiat, Tokyo 113, Japan
6.Massachusetts Gen Hosp, Psychiat Serv, Boston, MA 02114 USA
7.Harvard Inst Psychiat Epidemiol & Genet, Boston, MA USA
8.Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA
9.Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA
10.Brockton W Roxbury Vet Affairs Med Ctr, Brockton, MA USA
推荐引用方式
GB/T 7714
Takahashi, S,Cui, YH,Kojima, T,et al. Family-based association study of markers on chromosome 22 in schizophrenia using African-American, European-American, and Chinese families[J]. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS,2003,120B(1):11-17.
APA Takahashi, S.,Cui, YH.,Kojima, T.,Han, YH.,Zhou, RL.,...&Tsuang, MT.(2003).Family-based association study of markers on chromosome 22 in schizophrenia using African-American, European-American, and Chinese families.AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS,120B(1),11-17.
MLA Takahashi, S,et al."Family-based association study of markers on chromosome 22 in schizophrenia using African-American, European-American, and Chinese families".AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS 120B.1(2003):11-17.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Takahashi, S]的文章
[Cui, YH]的文章
[Kojima, T]的文章
百度学术
百度学术中相似的文章
[Takahashi, S]的文章
[Cui, YH]的文章
[Kojima, T]的文章
必应学术
必应学术中相似的文章
[Takahashi, S]的文章
[Cui, YH]的文章
[Kojima, T]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。