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学科主题: 临床医学
题名:
Fused monochromatic imaging acquired by single source dual energy CT in hepatocellular carcinoma during arterial phase: an initial experience
作者: Gao, Shun-Yu; Zhang, Xiao-Peng; Cui, Yong; Sun, Ying-Shi; Tang, Lei; Li, Xiao-Ting; Zhang, Xiao-Yan; Shan, Jun
关键词: Computed tomography (CT) ; dual energy ; hepatocellular carcinoma (HCC) ; image postprocessing ; comparative study
刊名: CHINESE JOURNAL OF CANCER RESEARCH
发表日期: 2014-08-01
DOI: 10.3978/j.issn.1000-9604.2014.08.15
卷: 26, 期:4, 页:437-443
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Oncology
研究领域[WOS]: Oncology
关键词[WOS]: LOW TUBE VOLTAGE ; HYPERVASCULAR LIVER-TUMORS ; COMPUTED-TOMOGRAPHY ; CONTRAST ENHANCEMENT ; QUALITY ; PHANTOM ; FUSION ; NOISE ; MODE
英文摘要:

Objective: To explore whether single and fused monochromatic images can improve liver tumor detection and delineation by single source dual energy CT (ssDECT) in patients with hepatocellular carcinoma (HCC) during arterial phase.

Methods: Fifty-seven patients with HCC who underwent ssDECT scanning at Beijing Cancer Hospital were enrolled retrospectively. Twenty-one sets of monochromatic images from 40 to 140 keV were reconstructed at 5 keV intervals in arterial phase. The optimal contrast-noise ratio (CNR) monochromatic images of the liver tumor and the lowest-noise monochromatic images were selected for image fusion. We evaluated the image quality of the optimal-CNR monochromatic images, the lowest-noise monochromatic images and the fused monochromatic images, respectively. The evaluation indicators included the spatial resolution of the anatomical structure, the noise level, the contrast and CNR of the tumor.

Results: In arterial phase, the anatomical structure of the liver can be displayed most clearly in the 65-keV monochromatic images, with the lowest image noise. The optimal-CNR monochromatic images of HCC tumor were 50-keV monochromatic images in which the internal structural features of the liver tumors were displayed most clearly and meticulously. For tumor detection, the fused monochromatic images and the 50-keV monochromatic images had similar performances, and were more sensitive than 65-keV monochromatic images.

Conclusions: We achieved good arterial phase images by fusing the optimal-CNR monochromatic images of the HCC tumor and the lowest-noise monochromatic images. The fused images displayed liver tumors and anatomical structures more clearly, which is potentially helpful for identifying more and smaller HCC tumors.

语种: 英语
所属项目编号: 2011CB707705 ; 81371715 ; 81201215 ; Z121107001012115
项目资助者: National Basic Research Program of China (973 Program) ; National Natural Science Foundation of China ; Capital Characteristic Clinical Application Research
WOS记录号: WOS:000342482700014
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/50450
Appears in Collections:北京大学临床肿瘤学院_期刊论文

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作者单位: Peking Univ Canc Hosp & Inst, Key Lab Carcinogenesis & Translat Res, Minist Educ, Dept Radiol, Beijing 100142, Peoples R China

Recommended Citation:
Gao, Shun-Yu,Zhang, Xiao-Peng,Cui, Yong,et al. Fused monochromatic imaging acquired by single source dual energy CT in hepatocellular carcinoma during arterial phase: an initial experience[J]. CHINESE JOURNAL OF CANCER RESEARCH,2014,26(4):437-443.
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