IR@PKUHSC  > 北京大学临床肿瘤学院
学科主题临床医学
No impact of repeated endoscopic screens on gastric cancer mortality in a prospectively followed Chinese population at high risk
Riecken, B1; Pfeiffer, R1; Ma, JL1; Jin, ML1; Li, JY1; Liu, WD1; Zhang, L1; Chang, YS1; Gail, MH1; You, WC1
关键词Stomach Neoplasms Gastroscopy Mortality China
刊名PREVENTIVE MEDICINE
2002
DOI10.1006/pmed.2001.0925
34期:1页:22-28
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Public, Environmental & Occupational Health ; Medicine, General & Internal
研究领域[WOS]Public, Environmental & Occupational Health ; General & Internal Medicine
关键词[WOS]STOMACH-CANCER ; LESIONS ; JAPAN ; DIAGNOSIS ; PROGRAM ; DESIGN
英文摘要

Background. Gastric cancer (GC) is the leading cause of cancer deaths in China. Our study prospectively evaluated the impact of repeated endoscopic screens on GC mortality in a high-risk population in China.

Methods. Between 1989 and 1999, a population-based gastroscopic screening was conducted in 4,394 residents of Linqu County, China, a region with the highest rates of GC worldwide. Residents ages 35 to 64 years received initial gastroscopies with biopsies in 1989. Repeated endoscopies were performed in 1994 and 1999. Cancer occurrences and deaths were actively monitored throughout the entire period until July 2000. Mortality from GC was compared with expected values based on mortality rates obtained for Linqu in the 1990-1992 Chinese Cancer Mortality Survey.

Results. Between March 1989 and July 2000, 39,303 person-years were accumulated; 85 new GCs occurred, 29 (34.5%) were in early stage. Fifty-eight cases (68%) were identified at one of the screens. The number of observed deaths from GC (37) was close to the expected (36.8). The standardized mortality ratio was 1.01 (95% Cl 0.72-1.37) for the entire cohort, 1.13 (95% CI 0.77-1.57) for males, and 0.65 (95% C1 0.26-1.32) for females.

Conclusions. Despite high population coverage with repeated screens, no reduction in GC mortality was observed in this high-risk population in China.

语种英语
WOS记录号WOS:000173235300004
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被引频次:39[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/50471
专题北京大学临床肿瘤学院
作者单位1.NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA
2.Peking Univ, Beijing Inst Canc Res, Beijing 100036, Peoples R China
3.Peking Univ, Sch Oncol, Beijing 100036, Peoples R China
4.Freiburg Univ Hosp, Dept Gastroenterol & Hepatol, Freiburg, Germany
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Riecken, B,Pfeiffer, R,Ma, JL,et al. No impact of repeated endoscopic screens on gastric cancer mortality in a prospectively followed Chinese population at high risk[J]. PREVENTIVE MEDICINE,2002,34(1):22-28.
APA Riecken, B.,Pfeiffer, R.,Ma, JL.,Jin, ML.,Li, JY.,...&You, WC.(2002).No impact of repeated endoscopic screens on gastric cancer mortality in a prospectively followed Chinese population at high risk.PREVENTIVE MEDICINE,34(1),22-28.
MLA Riecken, B,et al."No impact of repeated endoscopic screens on gastric cancer mortality in a prospectively followed Chinese population at high risk".PREVENTIVE MEDICINE 34.1(2002):22-28.
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