IR@PKUHSC  > 北京大学药学院  > 天然药物学系
学科主题药学
New aristolochic acid, aristololactam and renal cytotoxic constituents from the stem and leaves of Aristolochia contorta
Zhang, CY1; Wang, X1; Su, T1; Ma, CM1; Wen, YJ1; Shang, MY1; Li, XM1; Liu, GX1; Cai, SQ1
刊名PHARMAZIE
2005-10-01
60期:10页:785-788
收录类别SCI ; IC
文章类型Article
WOS标题词Science & Technology
类目[WOS]Chemistry, Medicinal ; Chemistry, Multidisciplinary ; Pharmacology & Pharmacy
研究领域[WOS]Pharmacology & Pharmacy ; Chemistry
英文摘要

Two novel phenanthrene derivatives, aristololactam IVa (1) and 9-hydroxy aristolochic acid 1 (2) were isolated from the stem and leaves of Aristolochia contorta Bunge, together with 17 known compounds (3-19). The structures of these compounds were determined by spectroscopic analysis. The phenanthrenes obtained were tested for cytotoxicity against renal proximal tubular epithelial cell line (HK-2). Aristololactam IVa and 7-methoxy aristololactam IV were found to have strong cytotoxic activity against HK-2 cells with a potency similar to or even stronger than those of aristolochic acid I and aristololactam 1.

语种英语
WOS记录号WOS:000232585400013
引用统计
被引频次:13[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/50516
专题北京大学药学院_天然药物学系
北京大学第一临床医学院_肾脏内科
作者单位1.Peking Univ, Sch Pharmaceut Sci, Dept Nat Med, Beijing 100871, Peoples R China
2.Peking Univ, Hosp 1, Dept Med, Beijing 100871, Peoples R China
推荐引用方式
GB/T 7714
Zhang, CY,Wang, X,Su, T,et al. New aristolochic acid, aristololactam and renal cytotoxic constituents from the stem and leaves of Aristolochia contorta[J]. PHARMAZIE,2005,60(10):785-788.
APA Zhang, CY.,Wang, X.,Su, T.,Ma, CM.,Wen, YJ.,...&Cai, SQ.(2005).New aristolochic acid, aristololactam and renal cytotoxic constituents from the stem and leaves of Aristolochia contorta.PHARMAZIE,60(10),785-788.
MLA Zhang, CY,et al."New aristolochic acid, aristololactam and renal cytotoxic constituents from the stem and leaves of Aristolochia contorta".PHARMAZIE 60.10(2005):785-788.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Zhang, CY]的文章
[Wang, X]的文章
[Su, T]的文章
百度学术
百度学术中相似的文章
[Zhang, CY]的文章
[Wang, X]的文章
[Su, T]的文章
必应学术
必应学术中相似的文章
[Zhang, CY]的文章
[Wang, X]的文章
[Su, T]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。