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Phage Display Applications for Molecular Imaging
Cai, Jiong1,2; Liu, Zhaofei3; Wang, Fan3; Li, Fang1,2
关键词Phage Display Molecular Imaging Tumor Peptide Antibody
刊名CURRENT PHARMACEUTICAL BIOTECHNOLOGY
2010-09-01
11期:6页:603-609
收录类别SCI
文章类型Review
WOS标题词Science & Technology
类目[WOS]Biochemistry & Molecular Biology ; Pharmacology & Pharmacy
研究领域[WOS]Biochemistry & Molecular Biology ; Pharmacology & Pharmacy
关键词[WOS]MEDULLARY-THYROID CARCINOMA ; CARBONIC-ANHYDRASE-IX ; TUMOR-HOMING PEPTIDE ; IN-VIVO ; BINDING PEPTIDE ; APOPTOSIS ; CANCER ; CELLS ; TECHNOLOGY ; LIBRARIES
英文摘要

The advancement of molecular imaging hardware and disease targets has driven the demand of novel probes for diagnosis of human diseases. The high-throughput property of phage-display techniques makes the fast developments of these probes possible. The antibody and peptide phage display libraries have been widely used in ligand-selections for a variety of targets in tumors including osteosarcomas, pancreatic ductal adenocarcinomas, thyroid, head and neck squamous cell carcinomas, prostate, bladder, colon and gastric cancers. The phage display techniques also have been utilized in development of imaging agents for tumor therapy response, apoptosis, hypoxia, infection and inflammation, Alzheimer′s diseases, diabetes and cardiovascular diseases.

语种英语
WOS记录号WOS:000281435100007
项目编号30670741 ; 30870728 ; 20820102035 ; 30930030 ; 30900373 ; 2007AA02Z467 ; 2009ZX09103-733 ; 2009ZX09103-746 ; 2009ZX09301-010
资助机构NSFC ; "863" project ; Ministry of Science and Technology of China
引用统计
被引频次:9[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/50547
专题北京大学医药卫生分析中心
北京大学基础医学院
作者单位1.Peking Union Med Coll, Peking Union Med Coll Hosp, Dept Nucl Med, Beijing 100730, Peoples R China
2.Chinese Acad Med Sci, Beijing 100730, Peoples R China
3.Peking Univ, Med Isotopes Res Ctr, Beijing 100191, Peoples R China
推荐引用方式
GB/T 7714
Cai, Jiong,Liu, Zhaofei,Wang, Fan,et al. Phage Display Applications for Molecular Imaging[J]. CURRENT PHARMACEUTICAL BIOTECHNOLOGY,2010,11(6):603-609.
APA Cai, Jiong,Liu, Zhaofei,Wang, Fan,&Li, Fang.(2010).Phage Display Applications for Molecular Imaging.CURRENT PHARMACEUTICAL BIOTECHNOLOGY,11(6),603-609.
MLA Cai, Jiong,et al."Phage Display Applications for Molecular Imaging".CURRENT PHARMACEUTICAL BIOTECHNOLOGY 11.6(2010):603-609.
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