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The orphan nuclear receptors, estrogen receptor-related receptors: Their role as new biomarkers in gynecological cancer
Sun, PM1; Wei, LH1; Denkert, C1; Lichtenegger, W1; Sehouli, J1
关键词Orphan Nuclear Receptors Err Er Cross-talk Biomarker Review
刊名ANTICANCER RESEARCH
2006-03-01
26期:2C页:1699-1706
收录类别ISTP ; SCI
文章类型Proceedings Paper
WOS标题词Science & Technology
类目[WOS]Oncology
研究领域[WOS]Oncology
关键词[WOS]ALPHA ERR-ALPHA ; HUMAN LACTOFERRIN GENE ; RESPONSE ELEMENTS ; TRANSCRIPTIONAL ACTIVATION ; BREAST-CANCER ; EXPRESSION ; GAMMA ; PROMOTER ; BETA ; COACTIVATOR
英文摘要

The family of estrogen receptor-related receptors (ERRs) is a subfamily of the orphan nuclear receptors, which is closely related to the estrogen receptor (ER) family. Research on ERRs has shown that the ERR family share target genes, co-regulators and promoters with the E R family. ERRs seem to interfere with the classic ER-mediated estrogen responsive signaling in various ways. Moreover, ERRs have been reported to be prognostic biomarkers in breast, ovarian and colorectal cancer. ERRs should be considered as additional factors in the evaluation of gynecological tumors. Since ERRs have an important influence on the overall estrogenic response, they are of clinical importance in gynecological cancer, but also regarding women′s general health.

语种英语
WOS记录号WOS:000236684100005
引用统计
被引频次:7[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/50557
专题北京大学第二临床医学院
作者单位1.Peking Univ, Peoples Hosp, Dept Gynecol Oncol, Beijing 100044, Peoples R China
2.Univ Med Berlin, Charite, Dept Obstet & Gynecol, D-13353 Berlin, Germany
3.Univ Med Berlin, Charite, Inst Pathol, D-10117 Berlin, Germany
推荐引用方式
GB/T 7714
Sun, PM,Wei, LH,Denkert, C,et al. The orphan nuclear receptors, estrogen receptor-related receptors: Their role as new biomarkers in gynecological cancer[J]. ANTICANCER RESEARCH,2006,26(2C):1699-1706.
APA Sun, PM,Wei, LH,Denkert, C,Lichtenegger, W,&Sehouli, J.(2006).The orphan nuclear receptors, estrogen receptor-related receptors: Their role as new biomarkers in gynecological cancer.ANTICANCER RESEARCH,26(2C),1699-1706.
MLA Sun, PM,et al."The orphan nuclear receptors, estrogen receptor-related receptors: Their role as new biomarkers in gynecological cancer".ANTICANCER RESEARCH 26.2C(2006):1699-1706.
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