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学科主题: 临床医学
题名:
A modified GEWF solution is cost-saving and effective for lymph node retrieval in resected colorectal carcinoma specimens
作者: Ma, Xiao-Long; Ye, Ju-Xiang; Su, Jing; Qi, Fei-Fei; Meng, Qing-Yang; Shi, Xue-Ying
关键词: Lymph node revealing solution ; Recycled alcohol ; Eosin ; Colorectal carcinoma ; Staging
刊名: PATHOLOGY RESEARCH AND PRACTICE
发表日期: 2014
DOI: 10.1016/j.prp.2014.05.004
卷: 210, 期:9, 页:543-547
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Pathology
研究领域[WOS]: Pathology
关键词[WOS]: MINIMUM NUMBER ; COLON-CANCER ; CLEARANCE TECHNIQUE ; REVEALING SOLUTION ; FAT CLEARANCE ; IMPACT ; ADENOCARCINOMA ; RECOMMENDATION ; DISSECTION ; RECOVERY
英文摘要:

Lymph node (LN) retrieval is important for proper staging of colorectal carcinoma. Although various assistant techniques were recommended to facilitate LN identification, most of them were unavoidably time-consuming, resource intensive and costly.

We prepared a modified GEWF solution (RE-GEWF) by use of recycled alcohol and a familiar dye, eosin and investigated its efficacy on 55 colorectal carcinoma specimens. Of the 55 studied cases, 33 of them with <12 LNs (Group A) and 22 with >= 12 LNs were detected (Group B) before RE-GEWF treatment. All were subsequently treated with RE-GEWF for 14-16 h and were inspected again for LNs.

The number of LNs revealed before and after RE-GEWF treatment was 539 and 476 respectively. The mean number of LNs per cases increased from 9.80 +/- 6.27 to 18.43 +/- 8.77. Twelve accessory LN metastases were found in 9 cases. Upgrade of pN stage was only present in 7 of the Group A cases.

The results show that RE-GEWF is as effective as other reported LN revealing solutions. Use of RE-GEWF not only can assure the quality of LN detection, but also minimize the cost and reduce the release of waste. (C) 2014 Elsevier GmbH. All rights reserved.

语种: 英语
WOS记录号: WOS:000342247300001
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/50564
Appears in Collections:北京大学第三临床医学院_病理科_期刊论文

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作者单位: Peking Univ, Dept Pathol, Hosp 3, Sch Basic Med Sci,Hlth Sci Ctr, Beijing 100191, Peoples R China

Recommended Citation:
Ma, Xiao-Long,Ye, Ju-Xiang,Su, Jing,et al. A modified GEWF solution is cost-saving and effective for lymph node retrieval in resected colorectal carcinoma specimens[J]. PATHOLOGY RESEARCH AND PRACTICE,2014,210(9):543-547.
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