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学科主题: 临床医学
题名:
Paraneoplastic pemphigus associated with Castleman tumor - A commonly reported subtype of paraneoplastic pemphigus in China
作者: Wang, J1; Zhu, XJ1; Li, RY1; Tu, P1; Wang, R1; Zhang, LB1; Li, T1; Chen, XX1; Wang, AP1; Yang, SX1; Wu, Y1; Yang, HZ1; Ji, SZ1
刊名: ARCHIVES OF DERMATOLOGY
发表日期: 2005-10-01
卷: 141, 期:10, 页:1285-1293
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Dermatology
研究领域[WOS]: Dermatology
关键词[WOS]: LYMPH-NODE HYPERPLASIA ; EROSIVE LICHEN-PLANUS ; BRONCHIOLITIS OBLITERANS ; DISEASE ; VULGARIS ; DISORDERS ; AUTOANTIBODY
英文摘要:

Background: Castleman tumor, a rare lymphoproliferative disorder, is one of the associated tumors in paraneoplastic pemphigus. We analyzed the characteristics of a group of patients with Castleman tumor to clearly understand and to improve the prognosis of the disease.

Observations: Ten cases of paraneoplastic pemphigus associated with Castleman tumor treated in the Department of Dermatology, Peking University First Hospital, Beijing, China, from May 1, 1999, to March 31, 2004, were analyzed for clinical aspects, characteristics and histologic features of the tumors, and computed tomographic findings. Literature was reviewed and data were compared with our cases. Castleman tumor was a frequently reported neoplasm in association with paraneoplastic pemphigus in China. The disease was found to be caused by an autoimmune reaction originating from the B lymphocytes in the Castleman tumor.

Conclusions: Castleman tumor in association with paraneoplastic pemphigus is a commonly reported subtype of paraneoplastic pemphigus in China. Early detection and removal of the Castleman tumor are crucial for the treatment of this tumor-associated autoimmune disease.

语种: 英语
WOS记录号: WOS:000232503100013
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/50594
Appears in Collections:北京大学第一临床医学院_皮肤性病科_期刊论文

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作者单位: 1.Peking Univ, Hosp 1, Dept Dermatol, Beijing 100034, Peoples R China
2.Peking Univ, Hosp 1, Dept Med Images, Beijing 100034, Peoples R China
3.Peking Univ, Hosp 1, Dept Surg, Beijing 100034, Peoples R China
4.Peking Univ, Hosp 1, Dept Pathol, Beijing 100034, Peoples R China

Recommended Citation:
Wang, J,Zhu, XJ,Li, RY,et al. Paraneoplastic pemphigus associated with Castleman tumor - A commonly reported subtype of paraneoplastic pemphigus in China[J]. ARCHIVES OF DERMATOLOGY,2005,141(10):1285-1293.
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