IR@PKUHSC  > 北京大学第一临床医学院  > 放射治疗科
学科主题临床医学
Effects of diffusion time and diffusion gradient strength on the mean diffusivity of water molecules in healthy human brain
Gao Song1; Wang Xiaoying1; Bao Shanglian1
关键词Diffusion Time Diffusion Gradient Strength Diffusion-weighted Imaging Diffusion Tensor Imaging Mean Diffusivity
刊名PROGRESS IN NATURAL SCIENCE
2006-07-01
16期:7页:706-711
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Materials Science, Multidisciplinary ; Multidisciplinary Sciences
研究领域[WOS]Materials Science ; Science & Technology - Other Topics
关键词[WOS]WHITE-MATTER ; SELF-DIFFUSION ; TENSOR ; ECHO ; NMR ; COEFFICIENT ; IMAGES
英文摘要

Diffusion time and diffusion gradient strength are two important parameters of pulsed gradient spin echo (PGSE) that is the most commonly used method in diffusion-weighted magnetic resonance imaging. However, the effects of the diffusion time on the mean diffusivity (MD) in previous studies are controversial. In this study, a new experimental protocol was designed to evaluate the effects of the two parameters on the results of PGSE. It was found that MD decreased significantly with the increased diffusion time or increased diffusion gradient strength, which cannot be explained by the previous theories. Through theoretical analysis, we found the flaw in the pulsed gradient spin echo (PGSE) method, which is the explanation for the controversial results of diffusion time obtained by others.

语种英语
WOS记录号WOS:000239697500006
Citation statistics
Cited Times:5[WOS]   [WOS Record]     [Related Records in WOS]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/50599
Collection北京大学第一临床医学院_放射治疗科
作者单位1.Peking Univ, Lab Med Phys & Engn, Beijing 100871, Peoples R China
2.Peking Univ, Affiliated Hosp 1, Dept Radiol, Beijing 100034, Peoples R China
Recommended Citation
GB/T 7714
Gao Song,Wang Xiaoying,Bao Shanglian. Effects of diffusion time and diffusion gradient strength on the mean diffusivity of water molecules in healthy human brain[J]. PROGRESS IN NATURAL SCIENCE,2006,16(7):706-711.
APA Gao Song,Wang Xiaoying,&Bao Shanglian.(2006).Effects of diffusion time and diffusion gradient strength on the mean diffusivity of water molecules in healthy human brain.PROGRESS IN NATURAL SCIENCE,16(7),706-711.
MLA Gao Song,et al."Effects of diffusion time and diffusion gradient strength on the mean diffusivity of water molecules in healthy human brain".PROGRESS IN NATURAL SCIENCE 16.7(2006):706-711.
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