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学科主题: 临床医学
题名:
Clinical features of hyperadrenergic postural tachycardia syndrome in children
作者: Zhang, Qingyou1; Chen, Xia2; Li, Jiawei1; Du, Junbao1
关键词: children ; hyperadrenergic ; postural tachycardia syndrome
刊名: PEDIATRICS INTERNATIONAL
发表日期: 2014-12-01
DOI: 10.1111/ped.12392
卷: 56, 期:6, 页:813-816
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Pediatrics
研究领域[WOS]: Pediatrics
关键词[WOS]: ORTHOSTATIC TACHYCARDIA ; BLOOD-PRESSURE ; HEART-RATE ; INTOLERANCE ; ADOLESCENTS ; NOREPINEPHRINE ; EXPERIENCE ; MANAGEMENT ; PEDIATRICS
英文摘要:

BackgroundHyperadrenergic postural tachycardia syndrome (POTS) is the main phenotype of POTS. The aim of this study was to present our single-center experience of hyperadrenergic POTS in children and adolescents.

MethodsThirty-seven patients who met the diagnostic criteria for POTS were enrolled in our study. Their orthostatic serum norepinephrine levels were determined by high-performance liquid chromatography. In a retrospective analysis, based on clinical and serum norepinephrine criteria, we analyzed the clinical features of POTS cases between the POTS-alone group and the hyperadrenergic POTS group.

ResultsNineteen patients (51.35%) met the diagnostic criteria for hyperadrenergic POTS and 18 patients were assigned to the POTS-alone group. Compared with the POTS-alone patients, dizziness, headache and tremulousness were more frequent in patients with hyperadrenergic POTS (P < 0.05). During the tilt table test, children with hyperadrenergic POTS had a greater increment of systolic blood pressure and heart rate than POTS-alone patients.

ConclusionPatients with hyperadrenergic POTS should be identified and differentiated from those with neuropathic POTS. Hyperadrenergic POTS in children and adolescents should be considered when POTS patients suffer from frequent dizziness, headache, and tremulousness. In head-up tilt testing, children and adolescents with hemodynamic characteristics of hyperadrenergic POTS had greater increments of systolic blood pressure and heart rate.

语种: 英语
所属项目编号: D121107001012051 ; 2012BAI03B03 ; 2012CB517806
项目资助者: Beijing Municipal Science &amp ; Technology Commission, China ; National Twelfth 5-Year Plan for Science and Technology Support ; Major Basic Research Project of China
WOS记录号: WOS:000346700900011
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/50608
Appears in Collections:北京大学第一临床医学院_儿科_期刊论文

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作者单位: 1.Peking Univ, Hosp 1, Dept Pediat, Beijing 100034, Peoples R China
2.Langfang Municipal Peoples Hosp, Dept Pediat, Langfang, Hebei, Peoples R China

Recommended Citation:
Zhang, Qingyou,Chen, Xia,Li, Jiawei,et al. Clinical features of hyperadrenergic postural tachycardia syndrome in children[J]. PEDIATRICS INTERNATIONAL,2014,56(6):813-816.
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