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学科主题临床医学
Clinical features of hyperadrenergic postural tachycardia syndrome in children
Zhang, Qingyou1; Chen, Xia2; Li, Jiawei1; Du, Junbao1
关键词Children Hyperadrenergic Postural Tachycardia Syndrome
刊名PEDIATRICS INTERNATIONAL
2014-12-01
DOI10.1111/ped.12392
56期:6页:813-816
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Pediatrics
研究领域[WOS]Pediatrics
关键词[WOS]ORTHOSTATIC TACHYCARDIA ; BLOOD-PRESSURE ; HEART-RATE ; INTOLERANCE ; ADOLESCENTS ; NOREPINEPHRINE ; EXPERIENCE ; MANAGEMENT ; PEDIATRICS
英文摘要

BackgroundHyperadrenergic postural tachycardia syndrome (POTS) is the main phenotype of POTS. The aim of this study was to present our single-center experience of hyperadrenergic POTS in children and adolescents.

MethodsThirty-seven patients who met the diagnostic criteria for POTS were enrolled in our study. Their orthostatic serum norepinephrine levels were determined by high-performance liquid chromatography. In a retrospective analysis, based on clinical and serum norepinephrine criteria, we analyzed the clinical features of POTS cases between the POTS-alone group and the hyperadrenergic POTS group.

ResultsNineteen patients (51.35%) met the diagnostic criteria for hyperadrenergic POTS and 18 patients were assigned to the POTS-alone group. Compared with the POTS-alone patients, dizziness, headache and tremulousness were more frequent in patients with hyperadrenergic POTS (P < 0.05). During the tilt table test, children with hyperadrenergic POTS had a greater increment of systolic blood pressure and heart rate than POTS-alone patients.

ConclusionPatients with hyperadrenergic POTS should be identified and differentiated from those with neuropathic POTS. Hyperadrenergic POTS in children and adolescents should be considered when POTS patients suffer from frequent dizziness, headache, and tremulousness. In head-up tilt testing, children and adolescents with hemodynamic characteristics of hyperadrenergic POTS had greater increments of systolic blood pressure and heart rate.

语种英语
WOS记录号WOS:000346700900011
项目编号D121107001012051 ; 2012BAI03B03 ; 2012CB517806
资助机构Beijing Municipal Science &amp ; Technology Commission, China ; National Twelfth 5-Year Plan for Science and Technology Support ; Major Basic Research Project of China
引用统计
被引频次:1[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/50608
专题北京大学第一临床医学院_儿科
作者单位1.Peking Univ, Hosp 1, Dept Pediat, Beijing 100034, Peoples R China
2.Langfang Municipal Peoples Hosp, Dept Pediat, Langfang, Hebei, Peoples R China
推荐引用方式
GB/T 7714
Zhang, Qingyou,Chen, Xia,Li, Jiawei,et al. Clinical features of hyperadrenergic postural tachycardia syndrome in children[J]. PEDIATRICS INTERNATIONAL,2014,56(6):813-816.
APA Zhang, Qingyou,Chen, Xia,Li, Jiawei,&Du, Junbao.(2014).Clinical features of hyperadrenergic postural tachycardia syndrome in children.PEDIATRICS INTERNATIONAL,56(6),813-816.
MLA Zhang, Qingyou,et al."Clinical features of hyperadrenergic postural tachycardia syndrome in children".PEDIATRICS INTERNATIONAL 56.6(2014):813-816.
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