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IR@PKUHSC  > 北京大学精神卫生研究所  > 期刊论文
学科主题: 精神卫生
题名:
Recovery from psychotic illness: a 15-and 25-year international follow-up study
作者: Harrison, G1; Hopper, K1; Craig, T1; Laska, E1; Siegel, C1; Wanderling, J1; Dube, KC1; Ganev, K1; Giel, R1; An der Heiden, W1; Holmberg, SK1; Janca, A1; Lee, PWH1; Leon, CA1; Malhotra, S1; Marsella, AJ1; Nakane, Y1; Sartorius, N1; Shen, Y1; Skoda, C1; Thara, R1; Tsirkin, SJ1; Varma, VK1; Walsh, D1; Wiersma, D1
刊名: BRITISH JOURNAL OF PSYCHIATRY
发表日期: 2001-06-01
卷: 178, 页:506-517
收录类别: SCI ; SSCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Psychiatry
研究领域[WOS]: Psychiatry
关键词[WOS]: SEVERE MENTAL-ILLNESS ; SCHIZOPHRENIA ; PREDICTION ; DISORDERS ; COUNTRIES ; COHORT
英文摘要:

Background Poorly defined cohorts and weak study designs have hampered cross-cultural comparisons of course and outcome in schizophrenia.

Aims To describe long-term outcome in 18 diverse treated incidence and prevalence cohorts. To compare mortality, 15- and 25-year illness trajectory and the predictive strength of selected baseline and short-term course variables.

Method Historic prospective study. Standardised assessments of course and outcome.

Results About 75% traced. About 50% of surviving cases had favourable outcomes, but there was marked heterogeneity across geographic centres. In regression models, early (2-year) course patterns were the strongest predictor of 15-year outcome, but recovery varied by location; 16% of early unremitting cases achieved late-phase recovery.

Conclusions A significant proportion of treated incident cases of schizophrenia achieve favourable long-term outcome. Sociocultural conditions appear to modify long-term course. Early intervention programmes focused on social as well as pharmacological treatments may realise longer-term gains.

Declaration of interest Funded by the Laureate Foundation, the World Health Organization and the participating centres (see Acknowledgements).

语种: 英语
WOS记录号: WOS:000169249800005
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/50611
Appears in Collections:北京大学精神卫生研究所_期刊论文

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作者单位: 1.WHO, Ctr Res & Training Mental Hlth, Agra, Uttar Pradesh, India
2.WHO, Div Mental Hlth, CH-1211 Geneva, Switzerland
3.WHO, Div Mental Hlth, CH-1211 Geneva, Switzerland
4.Hlth Res Board, Dublin, Ireland
5.Prague Psychiat Ctr, Psychiatr Demog Unit, Prague, Czech Republic
6.Schizophrenia Res Fdn, Madras, Tamil Nadu, India
7.St Lomans Hosp, Dublin, Ireland
8.WHO Collaborating Ctr, Sofia, Bulgaria
9.Cent Inst Mental Hlth, Schizophrenia Res Unit, D-6800 Mannheim, Germany
10.Univ Rochester, Rochester, NY USA
11.Univ Valle, Dept Psychiat, Cali, Colombia
12.Univ Hawaii, Dept Psychol, Honolulu, HI 96822 USA
13.Nagasaki Univ, Sch Med, Dept Neuropsychiat, Nagasaki 852, Japan
14.Univ Bristol, Div Psychiat, Bristol BS2 8DZ, Avon, England
15.Nathan S Kline Inst Psychiat Res, Orangeburg, NY 10962 USA
16.Indian Council Med Res, New Delhi, India
17.SUNY Stony Brook, Dept Psychiat & Behav Sci, Stony Brook, NY 11794 USA
18.Univ Groningen Hosp, Dept Social Psychiat, Groningen, Netherlands
19.Univ Hong Kong, Dept Psychiat, Hong Kong, Hong Kong, Peoples R China
20.Postgrad Inst Med Educ & Res, Dept Psychiat, Chandigarh 160012, India
21.Beijing Med Univ, Inst Mental Hlth, Beijing 100083, Peoples R China
22.Russian Acad Med Sci, Mental Hlth Res Ctr, Moscow 109801, Russia
23.Postgrad Inst Med Educ & Res, Dept Psychiat, Chandigarh 160012, India
24.Grad Sch Behav & Cognit Neurosci, Dept Psychiat, Groningen, Netherlands

Recommended Citation:
Harrison, G,Hopper, K,Craig, T,et al. Recovery from psychotic illness: a 15-and 25-year international follow-up study[J]. BRITISH JOURNAL OF PSYCHIATRY,2001,178:506-517.
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