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学科主题临床医学
Evaluation of syphilis serostatus on the safety of IVF treatment
Lin, Shengli1,2,3; Li, Rong1,2,3; Huang, Shuo1,2,3; Zhao, Lianming4; Li, Ming1,2,3; Li, Junsheng1,2,3; Zhu, Jinliang1,2,3; Zheng, Xiaoying1,2,3; Huang, Jin1,2,3; Liu, Ping1,2,3; Qiao, Jie1,2,3
关键词Ivf-et Syphilis Serostatus Pregnancy Outcomes
刊名REPRODUCTIVE BIOMEDICINE ONLINE
2014-12-01
DOI10.1016/j.rbmo.2014.09.001
29期:6页:756-760
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Obstetrics & Gynecology ; Reproductive Biology
研究领域[WOS]Obstetrics & Gynecology ; Reproductive Biology
关键词[WOS]MATERNAL SYPHILIS ; CULTURE-MEDIA ; PREGNANCY ; GUIDELINES ; EMBRYOS
英文摘要

An increasing number of infertile syphilis-infected individuals have turned to assisted reproductive technology; however, the safety of syphilis carrier serostatus on IVF and embryo transfer outcomes has not been evaluated. Data from 482 patients who delivered singletons were analysed. In the retrospective study, the rate of IVF and intracytoplasmic sperm injection fertilization was 79.50% +/- 17.57%/ 78.72% +/- 16.66% in the Treponema pallidum particle agglutination assay negative (TPPA-negative) and rapid plasma reagin negative (RPR-negative) group, 76.12% +/- 22.99%/ 74.05% +/- 20.31% in the TPPA-positive and RPR-negative group, and 75.66% +/- 21.72%/ 70.90% +/- 16.11% in the TPPA-positive and RPR-positive group. The clinical pregnancy rate was 39.79% in the TPPAnegative and RPR-negative group, 46.30% in the TPPA-positive and RPR-negative group, and 36.59% in the TPPA-positive and RPR-positive group. No significant differences were found between the groups. The neonatal gestational age and mean birth weight were not significantly different between the TPPA-negative and TPPA-positive groups. Multiple linear regression analysis also showed no association between TPPA serostatus and newborn birth weight and gestational age. The present retrospective study showed that TPPA and RPR serostatus did not affect the outcomes of IVF and embryo transfer. Syphilis-infected individuals can undergo IVF and embryo transfer cycles after penicillin treatment. (C) 2014 Published by Elsevier Ltd on behalf of Reproductive Healthcare Ltd.

语种英语
WOS记录号WOS:000345759300015
项目编号81200437 ; 81200413 ; 81100466
资助机构National Natural Science Foundation of China
引用统计
被引频次:2[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/50639
专题北京大学第三临床医学院_生殖医学中心
北京大学第三临床医学院_妇产科
作者单位1.Peking Univ, Dept Obstet & Gynecol, Reprod Med Ctr, Hosp 3, Beijing 100191, Peoples R China
2.Minist Educ, Key Lab Assisted Reprod, Beijing, Peoples R China
3.Beijing Key Lab Reprod Endocrinol & Assisted Repr, Beijing, Peoples R China
4.Peking Univ, Hosp 3, Dept Urol, Beijing 100191, Peoples R China
推荐引用方式
GB/T 7714
Lin, Shengli,Li, Rong,Huang, Shuo,et al. Evaluation of syphilis serostatus on the safety of IVF treatment[J]. REPRODUCTIVE BIOMEDICINE ONLINE,2014,29(6):756-760.
APA Lin, Shengli.,Li, Rong.,Huang, Shuo.,Zhao, Lianming.,Li, Ming.,...&Qiao, Jie.(2014).Evaluation of syphilis serostatus on the safety of IVF treatment.REPRODUCTIVE BIOMEDICINE ONLINE,29(6),756-760.
MLA Lin, Shengli,et al."Evaluation of syphilis serostatus on the safety of IVF treatment".REPRODUCTIVE BIOMEDICINE ONLINE 29.6(2014):756-760.
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